Results 171 to 180 of about 137,846 (394)

Serum glutamic oxalacetic transaminase in rheumatoid arthritis and certain rheumatoid musculoskeletal disorders [PDF]

, 1958
James H. Barr, Bertrand L. Stolzer, Carl H. Eisenbeis, John E. Kurtz, H. M. Margolis   +4 more
openalex   +1 more source

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

Advanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui, Furong Huang, Kun Fang, Jingyue Yan, Yuebao Zhang, Diana D. Kang, Yufan Zhou, Yue Zhao, Jeffrey I. Everitt, William Hankey, Andrew J Armstrong, Jiaoti Huang, Hongyan Wang, Victor X. Jin, Yizhou Dong, Qianben Wang   +15 more
wiley   +1 more source

Renal and Hepatic Dysfunction in Malaria Patients in Minna, North Central Nigeria [PDF]

, 2009
Information on kidney and liver involvement in malaria in Africa is still very scanty. Kidney and liver functions were assessed in 70 malaria patients using serum levels of creatinine and urea and urinary protein levels as test indicators of kidney ...
Ogbadoyi, EO, Tsado, RD
core   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

The Effect of De-Fatted Moringa Oleifera Seed Powder on Growth Rate and some Biochemical Parameters of Albino Rats

The Bioscientist, 2013
The nutritional and therapeutic properties of Moringa oleifera cannot be overemphasized, since all the parts of the plant (leaves, seeds, root, bark, pods etc.) have been reported to possess antibiotic, anti-hypertensive, anti-tumor and anti-oxidative ...
I. O Igwilo, T.J. Ogoke , S.N. Igwilo, S.C. Udedi, M.S Abdulsalami, C.S Okafor   +5 more
doaj  

Biocatalytic Transamination for the Asymmetric Synthesis of Pyridylalkylamines. Structural and Activity Features in the Reactivity of Transaminases

, 2016
A set of transaminases has been investigated for the biocatalytic amination of 1-(4-chloropyridin-2-yl)alkan-1-ones. The influence of the chain length of the n-1-alkanone at the C-2 position of the pyridine has been studied in the reaction with different
M. Lopez-Iglesias, Daniel González‐Martínez, V. Gotor, E. Busto, W. Kroutil, V. Gotor‐Fernández   +5 more
semanticscholar   +1 more source

Communications Among Neurocytes in Parkinson's Disease Regulated by Differential Metabolism and Blood‐Brain Barrier Traversing of Chiral Gold Cluster‐MOF Integrated Nanoparticles

Advanced Science, EarlyView.
This study have loaded chiral gold nanoclusters onto the inner and outer surfaces of ZIF and uncovers the biodistribution, metabolic variances, and therapeutic mechanism of chiral nanoparticles, providing deep insights into the nanobiological effects of chiral anti‐inflammatory nanomedicines in PD therapy for future clinical transformation.
Junyang Chen, Gaoxiang Xu, Runpu Shen, Jianzhong Xu, Congcong Lu, Xin Li, Qi Feng, Qing Li   +7 more
wiley   +1 more source

Scientific opinion on the safety of green tea catechins

EFSA Journal, 2018
The EFSA ANS Panel was asked to provide a scientific opinion on the safety of green tea catechins from dietary sources including preparations such as food supplements and infusions.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Birgit Dusemund, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Davide Arcella, Fabiola Pizzo, Camilla Smeraldi, Matthew Wright   +27 more
doaj   +1 more source

Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of Glioblastoma

Advanced Science, EarlyView.
A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo   +10 more
wiley   +1 more source

Changes in perioperative serum transaminase levels: predicting early recurrence after hepatectomy for hepatocellular carcinoma

Frontiers in Oncology
Background and purposeHepatocellular carcinoma (HCC) is associated with poor prognosis due to its high propensity for early postoperative recurrence.
Yingfei Wei, Guixiang Qian, Tao Meng, Zhong Tong   +3 more
doaj   +1 more source