Results 11 to 20 of about 145 (90)

Transcranial Focused Ultrasound Targeting the Amygdala May Increase Psychophysiological and Subjective Negative Emotional Reactivity in Healthy Older Adults

Biological Psychiatry Global Open Science
Background: The amygdala is highly implicated in an array of psychiatric disorders but is not accessible using currently available noninvasive neuromodulatory techniques. Low-intensity transcranial focused ultrasound (TFUS) is a neuromodulatory technique
Bianca Hoang-Dang, Sabrina E. Halavi, Natalie M. Rotstein, Norman M. Spivak, Nolan H. Dang, Luka Cvijanovic, Sonja H. Hiller, Mauricio Vallejo-Martelo, Benjamin M. Rosenberg, Andrew Swenson, Sergio Becerra, Michael Sun, Malina E. Revett, David Kronemyer, Rustin Berlow, Michelle G. Craske, Nanthia Suthana, Martin M. Monti, Tomislav D. Zbozinek, Susan Y. Bookheimer, Taylor P. Kuhn   +20 more
doaj   +3 more sources

Safety of focused ultrasound neuromodulation in humans with temporal lobe epilepsy

Brain Stimulation, 2021
Objective: Transcranial Focused Ultrasound (tFUS) is a promising new potential neuromodulation tool. However, the safety of tFUS neuromodulation has not yet been assessed adequately.
John M. Stern, Norman M. Spivak, Sergio A. Becerra, Taylor P. Kuhn, Alexander S. Korb, David Kronemyer, Négar Khanlou, Samuel D. Reyes, Martin M. Monti, Caroline Schnakers, Patricia Walshaw, Inna Keselman, Mark S. Cohen, William Yong, Itzhak Fried, Sheldon E. Jordan, Mark E. Schafer, Jerome Engel, Jr., Alexander Bystritsky   +18 more
doaj   +1 more source

A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer’s disease [PDF]

Ultrasonography, 2021
Purpose Increasing attention has been paid to low-intensity transcranial focused ultrasound (tFUS) for its potential therapeutic effects in Alzheimer's disease (AD). While preclinical studies have shown promising therapeutic effects of low-intensity tFUS
Hyeonseok Jeong, Jooyeon Jamie Im, Jong-Sik Park, Seung-Hee Na, Wonhye Lee, Seung-Schik Yoo, In-Uk Song, Yong-An Chung   +7 more
doaj   +1 more source

Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation

Nature Communications, 2021
Low-intensity transcranial focused ultrasound (tFUS) is a non-invasive neuromodulation technique with high spatial specificity. The authors show that excitatory and inhibitory neurons respond differently to tFUS, suggesting the possibility of ...
Kai Yu, Xiaodan Niu, Esther Krook-Magnuson, Bin He   +3 more
doaj   +1 more source

Transcranial Focused Ultrasound Neuromodulation: A Review of the Excitatory and Inhibitory Effects on Brain Activity in Human and Animals

Frontiers in Human Neuroscience, 2021
Non-invasive neuromodulation technology is important for the treatment of brain diseases. The effects of focused ultrasound on neuronal activity have been investigated since the 1920s.
Tingting Zhang, Tingting Zhang, Na Pan, Na Pan, Yuping Wang, Yuping Wang, Yuping Wang, Chunyan Liu, Chunyan Liu, Shimin Hu, Shimin Hu   +10 more
doaj   +1 more source

Transcranial Focused Ultrasound to the Right Prefrontal Cortex Improves Mood and Alters Functional Connectivity in Humans

Frontiers in Human Neuroscience, 2020
Transcranial focused ultrasound (tFUS) is an emerging method for non-invasive neuromodulation akin to transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).
Joseph L. Sanguinetti, Joseph L. Sanguinetti, Joseph L. Sanguinetti, Stuart Hameroff, Stuart Hameroff, Stuart Hameroff, Ezra E. Smith, Ezra E. Smith, Tomokazu Sato, Chris M. W. Daft, William J. Tyler, John J. B. Allen   +11 more
doaj   +1 more source

Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus

Brain Stimulation, 2022
Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj   +1 more source

Evaluating Transcranial Focused Ultrasound Stimulation (tFUS) for Targeted Neuromodulation in Generalized Anxiety Disorder: A Double-Blind Feasibility Study

Brain Stimulation
Morgan Dancy
exaly   +3 more sources

Excitatory‐inhibitory modulation of transcranial focus ultrasound stimulation on human motor cortex

CNS Neuroscience &Therapeutics, Volume 29, Issue 12, Page 3829-3841, December 2023., 2023
MRI‐guided tFUS with two sets of different parameters produces excitatory and inhibitory neuro‐modulatory effects on the human motor cortex. The potential mechanism may be to regulate the GABAergic and glutamatergic receptor function and neurotransmitter metabolic level.
Tingting Zhang, Bingqi Guo, Zhentao Zuo, Xiaojing Long, Shimin Hu, Siran Li, Xin Su, Yuping Wang, Chunyan Liu   +8 more
wiley   +1 more source

Numerical and experimental evaluation of low‐intensity transcranial focused ultrasound wave propagation using human skulls for brain neuromodulation

Medical Physics, Volume 50, Issue 1, Page 38-49, January 2023., 2023
Abstract Background Low‐intensity transcranial focused ultrasound (tFUS) has gained considerable attention as a promising noninvasive neuromodulatory technique for human brains. However, the complex morphology of the skull hinders scholars from precisely predicting the acoustic energy transmitted and the region of the brain impacted during the ...
Mengyue Chen, Chang Peng, Huaiyu Wu, Chih‐Chung Huang, Taewon Kim, Zachary Traylor, Marie Muller, Pratik Y. Chhatbar, Chang S. Nam, Wuwei Feng, Xiaoning Jiang   +10 more
wiley   +1 more source