Results 41 to 50 of about 145 (90)

Transcranial Focused Ultrasound Stimulation for Alzheimer’s Disease—A Scoping Review

Brain Sciences
Background/Objectives: Alzheimer’s disease (AD) remains a significant global health challenge, characterised by a persistent resistance to traditional pharmacological interventions. While non-invasive brain stimulation (NIBS) techniques like transcranial
Jon Crompton, Robyn Cuthell, Tom G. J. Steward, William W. Watts, Alanoud Alqahtani, Daniel J. Whitcomb   +5 more
doaj   +1 more source

Individualized transcranial focused ultrasound stimulation improves cognitive impairment in Alzheimer's disease patients by enhancing the default mode network

Alzheimer's &Dementia, Volume 21, Issue S3, December 2025.
Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and behavioral changes. Current treatment options are limited in their ability to halt or reverse disease progression, leading to a growing interest in non‐invasive neuromodulation techniques.
Jianwei Ge, Yi Ling, Benyan Luo
wiley   +1 more source

Restoration of Glymphatic Influx After Photothrombotic Stroke Using Low‐Intensity Focused Ultrasound

CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.
We examine immediate effect and 7‐day LIFU on CSF influx in stroke mice. LIFU rapidly increased CSF influx, peaking at 20–30 min post‐stimulation. Stroke reduced CSF influx, lowest at day 1‐3, with recovery by day 7. Daily contralesional LIFU restored CSF influx, suggesting stroke recovery benefits.
Ming‐Yen Hsiao, Yu‐Ling Lin, Meng‐Ting Lin, Wei‐Hao Liao, Wen‐Shiang Chen, Chueh‐Hung Wu   +5 more
wiley   +1 more source

TRPC4/TRPC5 are critical for neuronal modulation by transcranial focused ultrasound in retrosplenial cortex in male mice

Nature Communications
Transcranial focused ultrasound (tFUS) enables non-invasive neuromodulation, yet its underlying molecular mechanisms remain largely elusive. Here, we show that transient receptor potential canonical 4 (TRPC4) and transient receptor potential canonical 5 (
Cheng Wu, Jie You, Tao Sheng, Guo-Feng Li, Can Zhang, Li Liu, Li-Zhen Xu, Wei Xiong, Fan Yang, Wei Yang, Wei-Bao Qiu, Hai-Rong Zheng, Xiang-Yao Li   +12 more
doaj   +1 more source

Effects of transcranial focused ultrasound on human primary motor cortex using 7T fMRI: a pilot study

BMC Neuroscience, 2018
Background Transcranial focused ultrasound (tFUS) is a new non-invasive neuromodulation technique that uses mechanical energy to modulate neuronal excitability with high spatial precision.
Leo Ai, Priya Bansal, Jerel K. Mueller, Wynn Legon   +3 more
doaj   +1 more source

Wireless Power and Data Transfer Technologies for Flexible Bionic and Bioelectronic Interfaces: Materials and Applications

Advanced Materials Technologies, Volume 10, Issue 5, March 4, 2025.
This paper reviews the state‐of‐the‐art and recent advances in bio‐integrated wireless power and data transfer technologies for flexible bionics, wearable and implantable bioelectronics. The architectures, operating principles, materials, and application technologies are presented in detail.
Massimo Mariello, Christopher M. Proctor
wiley   +1 more source

Transcranial focused ultrasound to V5 enhances human visual motion brain-computer interface by modulating feature-based attention

Nature Communications
A brain-computer interface (BCI) enables users to control devices with their minds. Despite advancements, non-invasive BCIs still exhibit high error rates, prompting investigation into the potential reduction through concurrent targeted neuromodulation ...
Joshua Kosnoff, Kai Yu, Chang Liu, Bin He   +3 more
doaj   +1 more source

The mouse motor cortex stimulation via non-invasive temporal interference transcranial focused ultrasound with microbubbles

Ultrasonics Sonochemistry
Transcranial focused ultrasound (tFUS) has emerged as an innovative brain stimulation technology that uniquely integrates three characteristics: (a) non-invasive energy delivery, (b) submillimeter-scale spatial precision, and (c) effective penetration ...
Jie Jin, Xinze Liu, Zhenxiang Ji, Chenxuan Wu, Yuting Han, Quanrong Jing, Jian Zhang, Wei Li, Tianyi Yan, Hui Jing, Dingjie Suo   +10 more
doaj   +1 more source

A Wearable, Steerable, Transcranial Low‐Intensity Focused Ultrasound System

Journal of Ultrasound in Medicine, Volume 44, Issue 2, Page 239-261, February 2025.
Objectives Transcranial low‐intensity focused ultrasound (LIFU) offers unique opportunities for precisely neuromodulating small and/or deep targets within the human brain, which may be useful for treating psychiatric and neurological disorders. This article presents a novel ultrasound system that delivers focused ultrasound through the forehead to ...
Christopher R. Bawiec, Peter J. Hollender, Sarah B. Ornellas, Jessica N. Schachtner, Jacob F. Dahill‐Fuchel, Soren D. Konecky, John J. B. Allen   +6 more
wiley   +1 more source

Improving Targeting Specificity of Transcranial Focused Ultrasound in Subject Specific Head Models Using a Random Array Transducer: A k-Wave Simulation Study

IEEE Access
Transcranial focused ultrasound (tFUS) has emerged as a promising non-invasive modality for precision neuromodulation. However, the heterogeneous acoustic properties of the skull often induce phase aberrations that shift the ultrasound focus and ...
Zherui Li, Kai Yu, Joshua Kosnoff, Bin He   +3 more
doaj   +1 more source