Results 91 to 100 of about 199,711 (392)

Cortical Excitability as a Prognostic and Phenotypic Stratification Biomarker in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Despite its clinical heterogeneity, amyotrophic lateral sclerosis is unified by early and prominent alterations in cortical excitability, increasingly recognized as contributors to disease progression. This study assessed whether the ratio between motor evoked potential (MEP) amplitude, reflecting upper motor neuron integrity, and compound ...
Federico Ranieri, Gianmaria Senerchia, Luigi Bonan, Stefania Casali, Corrado Cabona, Mariagiovanna Cantone, Fabiola De Marchi, Luca Diamanti, Alberto Doretti, Nicola Fini, Massimiliano Filosto, Andrea Fortuna, Aniello Iovino, Valentina Virginia Iuzzolino, Giuseppe Lanza, Christian Lunetta, Luca Maderna, Jessica Mandrioli, Letizia Mazzini, Gabriella Musumeci, Andi Nuredini, Gianni Sorarù, Antonella Toriello, Nicola Ticozzi, Massimiliano Todisco, Veria Vacchiano, Lucia Zinno, Vincenzo Silani, Simone Rossi, Vincenzo Di Lazzaro, Raffaele Dubbioso, on behalf of the MND Study Group of the Italian Neurological Society (SIN) and the Neurostimulation‐Neuromodulation Study Group of the Italian Society of Clinical Neurophysiology (SINC), Francesca Calvi, Maria Caputo, Stefano Gazzina, Laura Filippi, Rachele Piras, Marilisa Boscarino, Rita Bella, Manuela Pennisi, Fabio Pilato, Rosa Iodice   +41 more
wiley   +1 more source

Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke

Journal of NeuroEngineering and Rehabilitation, 2022
Objectives This systematic review and meta-analysis aim to summarize and analyze the available evidence of non-invasive brain stimulation/spinal cord stimulation on gait, balance and/or lower limb motor recovery in stroke patients.
Jitka Veldema, Alireza Gharabaghi
doaj   +1 more source

Randomized Sham-Controlled Trial of Navigated Repetitive Transcranial Magnetic Stimulation for Motor Recovery in Stroke: The NICHE Trial

Stroke, 2018
Background and Purpose─ We aimed to determine whether low-frequency electric field navigated repetitive transcranial magnetic stimulation to noninjured motor cortex versus sham repetitive transcranial magnetic stimulation avoiding motor cortex could ...
R. Harvey, D. Edwards, K. Dunning, F. Fregni, J. Stein, Jarmo Laine, L. Rogers, Ford Vox, Ana Durand-Sanchez, Marcia A. Bockbrader, L. Goldstein, G. Francisco, C. Kinney, Charles Y Liu, S. Ryan, L. Morales-Quezada, L. Worthen-Chaudhari, D. Labar, Heidi M. Schambra, Carlyn R. Kappy, B. Kissela, W. Pratt   +21 more
semanticscholar   +1 more source

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

Advanced NanoBiomed Research, EarlyView.
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai, Bin Zhang, Hong Cheng, Yunzhu Huang, Xinyue Han, Yangnan Hu, Renjie Chai, Wei Cao   +7 more
wiley   +1 more source

rTMS improves dysphagia by inhibiting NLRP3 inflammasome activation and caspase-1 dependent pyroptosis in PD mice

npj Parkinson's Disease
High incidence, severe consequences, unclear mechanism, and poor treatment effect happened in Parkinson’s disease-related dysphagia. Repetitive transcranial magnetic stimulation is an effective treatment for dysphagia in Parkinson’s disease. However, the
Peiling Huang, Ziman Zhu, Wenshan Li, Rong Zhang, Yijia Chi, Weijun Gong   +5 more
doaj   +1 more source

Testing rTMS-Induced Neuroplasticity: A Single Case Study of Focal Hand Dystonia [PDF]

, 2018
Focal hand dystonia in musicians is a neurological motor disorder in which aberrant plasticity is caused by excessive repetitive use. This work's purposes were to induce plasticity changes in a dystonic musician through five daily thirty-minute sessions ...
Betti, Sonia, Castiello, Umberto, Sartori, Luisa, Spoto, Andrea   +3 more
core   +2 more sources

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3‐Way Crossover Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is approved as an adjunctive treatment of seizures associated with Dravet syndrome, Lennox–Gastaut Syndrome, and tuberous sclerosis. Its therapeutic and adverse effects are thought to arise, at least partly, from a pharmacokinetic interaction with clobazam, another anti‐seizure medication (ASM).
Andriy A. Gorbenko, Catherine M.K.E. de Cuba, Annika A. de Goede, Titiaan E. Post, Roman Bohoslavsky, Pamela K. Strugala, Jules A.A.C. Heuberger, Geert Jan Groeneveld   +7 more
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Prolonged transcranial magnetic stimulation in a pregnant patient with treatment-resistant depression: a case report

Journal of Medical Case Reports
Introduction Perinatal depression is a serious and highly prevalent medical condition in the USA. Nearly 85% of individuals with perinatal depression go untreated, leading to significant morbidity and mortality.
Rana Jawish, Marcela Smid, Adam Gordon, Kathleen Shangraw, Brian J. Mickey   +4 more
doaj   +1 more source

Superior parietal cortex and the attention to delayed intention: An rTMS study. [PDF]

, 2017
This study aimed to investigate whether the superior parietal cortex is causally involved in PM and, if so, what is its functional role. We applied repetitive transcranial magnetic stimulation (rTMS) to the left and right superior parietal cortex, and we
Bisiacchi, Patrizia, Cona, Giorgia, Marino, Giuliana   +2 more
core   +1 more source