Results 81 to 90 of about 70,695 (313)

Cerebellum to motor cortex paired associative stimulation induces bidirectional STDP-like plasticity in human motor cortex

, 2012
The cerebellum is crucially important for motor control and adaptation. Recent non-invasive brain stimulation studies have indicated the possibility to alter the excitability of the cerebellum and its projections to the contralateral motor cortex, with ...
Tsai, Chon-Haw, Chon-Haw Tsai, Ming-Kuei Lu, Lu, Ming-Kuei, Ulf Ziemann, Ziemann, Ulf   +5 more
core   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Global Trends and Advances in Traumatic Brain Injury

Brain Health, EarlyView.
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang, Xixian Liao, Jiyao Jiang, Guoyi Gao   +3 more
wiley   +1 more source

Online repetitive transcranial magnetic stimulation during working memory in younger and older adults: A randomized within-subject comparison.

PLoS ONE, 2019
Working memory is the ability to perform mental operations on information that is stored in a flexible, limited capacity buffer. The ability to manipulate information in working memory is central to many aspects of human cognition, but also declines with
L Beynel, S W Davis, C A Crowell, S A Hilbig, W Lim, D Nguyen, H Palmer, A Brito, A V Peterchev, B Luber, S H Lisanby, R Cabeza, L G Appelbaum   +12 more
doaj   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

Non-invasive brain stimulation in frontotemporal dementia: syndrome-specific signals and priorities for future trials

Frontiers in Aging Neuroscience
Frontotemporal dementia is the second most common cause of young-onset dementia after Alzheimer’s disease and lacks disease-modifying treatment. This narrative review summarizes human studies of non-invasive brain stimulation, including repetitive ...
Jingshu Wang, Xiaoshu Fu, Jiangru Liu, Yu Yang   +3 more
doaj   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery

Epilepsia Open, EarlyView.
Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields, Hunain Abri, Cemal Karakas, Shannon D. Davis, Ian S. Mutchnick   +4 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation [PDF]

Deutsches Ärzteblatt international, 2015
We think that this review (1) is in actual fact very relevant, but somewhat incomplete as it does not include repetitive transcranial magnetic stimulation (rTMS) as a treatment option. This method, though not approved in Germany, has been cleared for use in the United States and several European and non-European countries.
openaire   +2 more sources

Probing the mind with magnetism

, 2000
Transcranial magnetic stimulation is a technique that can be used to interfere reversibly with cortical processing. It creates a ‘virtual lesion’, which is relatively focal in space and time and can therefore be used to address questions beyond the scope
Stewart, Lauren, Lauren Stewart, Stewart, L, Walsh, V, Vincent Walsh, Walsh, Vincent   +5 more
core