Results 61 to 70 of about 473,414 (215)

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Contrast Enhanced Ultrasound of Pancreatic Tumours

, 2009
Learning Objectives To describe Contrast Enhanced Ultrasound (CEUS) findings that allow characterization of pancreatic tumours. Imaging Findings Ductal adenocarcinoma: poor enhancement appearing hypoechoic.
D'ONOFRIO, Mirko
core   +1 more source

A systematic review of preclinical and clinical transcranial ultrasound neuromodulation and opportunities for functional connectomics

Brain Stimulation
Background: Low-intensity transcranial ultrasound has surged forward as a non-invasive and disruptive tool for neuromodulation with applications in basic neuroscience research and the treatment of neurological and psychiatric conditions.
Carly Pellow, Samuel Pichardo, G Bruce Pike   +2 more
doaj   +1 more source

S-Nitrosoglutathione reduces asymptomatic embolization after carotid angioplasty [PDF]

, 2002
Background: The major complication of carotid angioplasty is embolic stroke, which may occur after balloon inflation and deflation or in the early postintervention period.
Clifton, A., Markus, H.S., Martin, J.F., Kaposzta, Z., Molloy, J.   +4 more
core  

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

An open-source phase correction toolkit for transcranial focused ultrasound

BMC Biomedical Engineering, 2020
Background The phase correction on transcranial focused ultrasound is essential to regulate unwanted focal point shift caused by skull bone aberration.
Changzhu Jin, David Moore, John Snell, Dong-Guk Paeng   +3 more
doaj   +1 more source

Rethinking clinical trials of transcranial direct current stimulation: Participant and assessor blinding is inadequate at intensities of 2mA [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Moseley G. Lorimer, Neil E O'Connell, John Cossar, Bunce, David, Wand Benedict M., Marston, L., Moseley, GL, Cossar, John, Wand, B.M., Cossar John, O'Connell, NE, Moseley, G.L., G Lorimer Moseley, Wand, BM, De, S.L.H., Bunce, D., Moseley, G Lorimer, Cossar, J, Marston Louise, O\u27Connell, Neil E, Wand, Benedict M, Marston, L, Benedict M Wand, Lorraine H De Souza, Louise Marston, David Bunce, O’Connell Neil E., Cossar, J., Bunce, D, Bunce David, De Souza, LH, Marston, Louise, De Souza, Lorraine H, O'Connell, N.E., De Souza Lorraine H.   +34 more
core   +1 more source