Results 331 to 340 of about 5,008,846 (367)
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Nucleosomes and transcription: recent lessons from genetics
Current Opinion in Genetics & Development, 1997Substantial evidence exists that nucleosomes affect transcription and that additional factors modify nucleosome function. Recent work has demonstrated that different types of histone mutants can be classified by their distinct effects on transcription in vivo.
Fred Winston, Grant A. Hartzog
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Genetic recombination of nucleosomal templates is mediated by transcription
Molecular and General Genetics MGG, 1994An in vitro system has been developed to examine the influence of transcription on genetic rearrangement. Using a homologous pairing assay, the transfer of one strand of a nucleosomal template onto a recipient DNA molecule was monitored as a function of RNA polymerase activity.
JoAnn Sekiguchi +3 more
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Transcription control reprogramming in genetic backup circuits
Nature Genetics, 2005A key question in molecular genetics is why severe mutations often do not result in a detectably abnormal phenotype. This robustness was partially ascribed to redundant paralogs that may provide backup for one another in case of mutation. Mining mutant viability and mRNA expression data in Saccharomyces cerevisiae, we found that backup was provided ...
Ran Kafri +2 more
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Towards Reverse Transcription with an Expanded Genetic Alphabet
ChemBioChem, 2019AbstractUnnatural base pairs (UBPs) strikingly augment the natural genetic alphabet. The development of particular hydrophobic UBPs even allows insertion and stable propagation in bacteria. Those UBPs expand the chemical scope of DNA and RNA, and thus, could enable the evolution of novel aptamers or ribozymes by in vitro selection (systematic evolution
Frank Eggert +3 more
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Genetic dissection of transcriptional regulation by cDNA‐AFLP
The Plant Journal, 2006SummaryThis study demonstrates that cDNA‐AFLP is a powerful gel‐based genome‐scale transcript profiling technique to generate quantitative gene expression profiles for eQTL mapping. We used cDNA‐AFLP to monitor the relative abundance of 912 transcripts across 50 Arabidopsis thaliana recombinant inbred lines.
Annelies Vercauteren +4 more
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Genetics of Energetics: Transcriptional Responses in Cardiac Metabolism
Annals of Biomedical Engineering, 2000Recent evidence suggests that energy substrate metabolism forms the link between gene expression and contractile function of the heart. This hypothesis draws on three seemingly unconnected observations, made in 1941 by three different investigators. The first gave rise to the concept of the dynamic nature of body constituents, the second to the concept
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A synthetic molecular system capable of mirror-image genetic replication and transcription.
Nature Chemistry, 2016Zimou Wang, Weiliang Xu, Lei Liu, T. Zhu
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Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Veda N Giri +2 more
exaly
From the genetic architecture to synaptic plasticity in autism spectrum disorder
Nature Reviews Neuroscience, 2015T. Bourgeron
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Martin G Pomper, Steven P Rowe
exaly