Results 121 to 130 of about 2,190,849 (297)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Micro-RNAs in breast cancer progression and metastasis: A chromatin and metabolic perspective

Heliyon
Breast cancer is a highly complex disease with multiple subtypes. While many of the breast cancer cases are sporadic some can be familial or hereditary.
Sweta Sikder, Aditya Bhattacharya, Aayushi Agrawal, Gautam Sethi, Tapas K. Kundu   +4 more
doaj   +1 more source

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

, 2005
Angela H. Ting, Kornel E. Schuebel, James G. Herman, Stephen B. Baylin   +3 more
openalex   +1 more source

Comprehensive analysis of NAC transcription factors uncovers their roles during fiber development and stress response in cotton [PDF]

, 2018
Heng Sun, Meiling Hu, Jianying Li, Lin Chen, Meng Li, Shuqin Zhang, Xianlong Zhang, Xiyan Yang   +7 more
openalex   +1 more source

Unraveling the role of MADS transcription factor complexes in apple tree dormancy [PDF]

, 2021
Vítor da Silveira Falavigna, Edouard Severing, Xuelei Lai, Joan Estevan, Isabelle Farrera, Véronique Hugouvieux, Luís Fernando Revers, Chloé Zubieta, George Coupland, Evelyne Costes, Fernando Andrés   +10 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The AREB1 Transcription Factor Influences Histone Acetylation to Regulate Drought Responses and Tolerance in Populus trichocarpa

, 2018
Shuang Li, Ying‐Chung Jimmy Lin, Pengyu Wang, Baofeng Zhang, Meng Li, Su Chen, Rui Shi, Sermsawat Tunlaya‐Anukit, Xinying Liu, Zhifeng Wang, Xiufang Dai, Jing Yu, Chenguang Zhou, Baoguang Liu, Jack Wang, Vincent L. Chiang, Wei Li   +16 more
openalex   +2 more sources

HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme [PDF]

, 2014
Marco Osterwalder, Dario Speziale, Malak Shoukry, Rajiv A. Mohan, Robert Ivánek, Manuel Kohler, Christian Beisel, Xiaohui Wen, Suzie J. Scales, Vincent M. Christoffels, Axel Visel, Javier López-Rı́os, Rolf Zeller   +12 more
openalex   +1 more source

Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis [PDF]

, 2021
Joseph Addison, Maria A. Voronkova, James H. Fugett, Chen‐Chung Lin, Nathaniel C. Linville, Brandon Trinh, Ryan H. Livengood, Matthew B. Smolkin, Michael D. Schaller, J. Michael Ruppert, Elena N. Pugacheva, Chad J. Creighton, Alexey V. Ivanov   +12 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source