Results 161 to 170 of about 2,206,258 (297)

SUMO Represses Transcriptional Activity of theDrosophilaSoxNeuro and Human Sox3 Central Nervous System–specific Transcription Factors

, 2005
Jean Savare, Nathalie Bonneaud, F Girard
openalex   +1 more source

Evidence that the regulation of diphtheria toxin production is directed at the level of transcription [PDF]

, 1978
J R Murphy, J L Michel, Mingxiang Teng
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Transcription termination counteracts DNA damage after WEE1 inhibition. [PDF]

Nucleic Acids Res
Landsverk HB, Sandquist LE, Bay LTE, Hauge S, van Bijsterveldt L, Lindbergsengen L, Lund-Andersen C, Kanduri C, Lyng H, Fjeldbo CS, Hompland T, Humphrey TC, Syljuåsen RG.   +12 more
europepmc   +1 more source

SMAD proteins of oligodendroglial cells regulate transcription of JC virus early and late genes coordinately with the Tat protein of human immunodeficiency virus type 1

, 2009
Michelle R. Stettner, Jonas A. Nance, Clayton Wright, Yayoi Kinoshita, Woong‐Ki Kim, Susan Morgello, Jay Rappaport, Kamel Khalili, Jennifer Gordon, Edward M. Johnson   +9 more
openalex   +2 more sources

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Genome-wide systematic characterization of <i>bZIP</i> transcription factors and their expression profiles during stem in tumorous stem mustard. [PDF]

PeerJ
Deng Y, Li F, Xie Y, Guo J, Shu J, Qin R, Sun Q, Wu K, Xu F, He X.   +9 more
europepmc   +1 more source

Simple, Rapid and Sensitive Portable Molecular Diagnosis of SFTS Virus Using Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP)

, 2018
Yun Hee Baek, Hyo-Soon Cheon, Su-Jin Park, Khristine Kaith S. Lloren, Su Jeong Ahn, Ju Hwan Jeong, Won-Suk Choi, Min-Ah Yu, Hyeok-il Kwon, Jin-Jung Kwon, Eun-Ha Kim, Young‐Il Kim, Khristine Joy C. Antigua, Seok-Yong Kim, Hye Won Jeong, Young Ki Choi, Min‐Suk Song   +16 more
openalex   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Characterizing Cell-Free Transcription and Translation Dynamics with Nucleic Acid-Based Assays. [PDF]

ACS Synth Biol
Piorino F, Sundberg C, Strychalski EA, Romantseva E.   +3 more
europepmc   +1 more source