Results 271 to 280 of about 3,372,915 (384)

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

FEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel, Maurice Tust, Samira Boussettaoui, Dietmar Fischer, Dirk Gründemann   +4 more
wiley   +1 more source

Integrated transcriptome and metabolome analysis provides insights into anthocyanin biosynthesis in Cichorium intybus L. [PDF]

BMC Plant Biol
Zhu M, Zhao R, Wu H, Zhang B, Zhang B, Han X.   +5 more
europepmc   +1 more source

Transcription of the genome of adenovirus type 12. I. Viral mRNA in abortively infected and transformed cells [PDF]

, 1975
Juan Ortı́n, Walter Doerfler
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

DNA-PKcs, a player winding and dancing with RNA metabolism and diseases. [PDF]

Cell Mol Biol Lett
Hou J, Lu M, Guo J, Wu J, Wang C, Zhou PK, Ma T.   +6 more
europepmc   +1 more source

Semi-conservative transcription in particles of a double-stranded RNA mycovirus [PDF]

, 1978
Giulio Ratti, K. W. Buck
openalex   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Transcription of single base oligonucleotides by ribonucleic acid-directed deoxyribonucleic acid polymerase [PDF]

, 1976
A.K. Falvey, Gary B. Weiss, Leslie J. Krueger, Judy Kantor, W. French Anderson   +4 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Sex-specific skeletal muscle gene expression responses to exercise reveal novel direct mediators of insulin sensitivity change. [PDF]

NAR Mol Med
Ma S, Hubal MJ, Morris MC, Ross LM, Huffman KM, Vann CG, Moore N, Hauser ER, Bareja A, Jiang R, Kummerfeld E, Barberio MD, Houmard JA, Bennett WC, Johnson JL, Timmons JA, Broderick G, Kraus VB, Aliferis CF, Kraus WE.   +19 more
europepmc   +1 more source