Results 181 to 190 of about 2,601,708 (287)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Editorial: Bacterial transcription factors and the cell cycle, volume II

open access: yesFrontiers in Microbiology, 2023
Morigen   +4 more
doaj   +1 more source

Benchmarking large language models for identifying transcription factor regulatory interactions. [PDF]

open access: yesBioinformatics
Noel L   +8 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

REPROGRAMMING ZFP189 TRANSCRIPTION FACTOR FUNCTION REGULATES DRUG SPECIFIC BEHAVIORAL RESPONSES AND TRANSCRIPTION

open access: yesIBRO Neuroscience Reports, 2023
Joseph Picone   +5 more
doaj   +1 more source

STAN, a computational framework for inferring spatially informed transcription factor activity. [PDF]

open access: yesNucleic Acids Res
Zhang L   +6 more
europepmc   +1 more source

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