Results 251 to 260 of about 14,240,467 (389)

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

open access: yesImmunity, 2011
Ruoning Wang   +10 more
semanticscholar   +1 more source

Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.

open access: hybrid, 1988
Shoji Hirashima   +3 more
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Structural basis of human Mediator recruitment by the phosphorylated transcription factor Elk-1. [PDF]

open access: yesNat Commun
Monté D   +6 more
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

Promoter decoding of transcription factor dynamics

open access: yesMolecular Systems Biology, 2013
Amie D Moody, Eric Batchelor
doaj   +1 more source

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