Results 261 to 270 of about 2,601,708 (287)

Transcription factor MITF regulates masseter muscle growth and development. [PDF]

Physiol Rep
Nariyama M, Ohnuki Y, Suita K, Ishikawa M, Matsubara R, Matsuo I, Mitsubayashi T, Mototani Y, Ito A, Abe M, Hayakawa Y, Nomura T, Wada S, Asada Y, Okumura S.   +14 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation. [PDF]

PLoS Biol
Vasseur L, Gheeraert C, Dubois-Chevalier J, Very N, Guille L, Bou Saleh M, Boulet C, Sobolewski C, Loyer P, Berthier A, Legrand N, Corlu A, Gnemmi V, Lasailly G, Leteurtre E, Galinousky D, Bongiovanni A, Taront S, Toft NI, Grøntved L, Tulasne D, Furlan A, Ntandja-Wandji LC, Staels B, Lefebvre P, Dubuquoy L, Eeckhoute J.   +26 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Pervasive binding of the stem cell transcription factor SALL4 shapes the chromatin landscape

Chhatbar K, Giuliani S, Quante T, Alexander-Howden B, Selfridge J, Guy J, Auchynnikava T, Spanos C, Mathieson T, Sanguinetti G, Bird A, Pantier R.   +11 more
europepmc   +1 more source

Development of Metabolite-Responsive Transcription Factor Systems as Modular Platforms for Gene Expression Control. [PDF]

Biosensors (Basel)
Ji H, Lee J, Song K, Jeon Y, Jang G, Yoon Y.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Epistatic contributions to human traits via transcription factor mechanisms

Roskams-Hieter B, Labayle O, Tetley-Campbell K, van der Laan MJ, Ponting CP, Beentjes SV, Khamseh A.   +6 more
europepmc   +1 more source

Mapping the transcriptional regulatory network of a fungal pathogen by exploiting transcription factor perturbation. [PDF]

mBio
Abid D, Brown H, Mateusiak C, Doering TL, Brent MR.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source