Results 271 to 280 of about 2,601,708 (287)

Transcription factor Zfx regulates tumor's evasion to T cell killing in immunotherapy. [PDF]

iScience
Kaufmann U, Wang J, Callow MG, Fortin JP, Myrta S, Nickles D, Reja R, Cheng E, Wonder E, Haley B, Liang Y, Martin S, Costa M, Huang H.   +13 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Defining transcription factor nucleosome binding with Pioneer-seq. [PDF]

PLoS Genet
Tsompana M, Wilson PD, Murugaiyan V, Handelmann CR, Buck MJ.   +4 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Novel Activators of the Transcription Factor PPARγ for Beef Quality through Molecular Modeling. [PDF]

ACS Omega
Nogueira AG, Mancini DT, Santos TMR, Ramalho TC.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

AraR Transcription Factor Affects the Sugar Metabolism and Acid Tolerance of <i>Lactiplantibacillus plantarum</i>. [PDF]

Foods
Zhao L, Chen M, Fu C, Pan T, Chen Q.
europepmc   +1 more source

Unraveling the Transcription Factor Code of Odontoblast Differentiation. [PDF]

J Dent Res
Lavický J, Lopez MG, Chochola V, Kompaníková P, Rakultsev V, Raška J, Winchester EW, Tuaima H, Englmaier L, Verner J, Švandová E, Buchtová M, Cotney J, Bryja V, Bohačiaková D, Bárta T, Krivanek J.   +16 more
europepmc   +1 more source

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]

Int J Mol Sci
Girón-Pérez MI, Ramírez-Ibarra KM, Covantes-Rosales CE, Girón-Pérez DA, Razura-Carmona FF, Contis-Montes de Oca A, Morales-Montor J, Pavón L, Toledo-Ibarra GA.   +8 more
europepmc   +1 more source

Transcription factor activator protein 4 (AP4)-mediated intrinsic control of axon regeneration. [PDF]

Sci Adv
Au NPB, Gan Y, Chen X, Gao F, Leung CK, Ma CHE.   +5 more
europepmc   +1 more source