Results 221 to 230 of about 1,348,561 (316)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Classifying the molecular functions of transcription factors beyond activation and repression. [PDF]

Genes Dev
Dong J, Guertin MJ.
europepmc   +1 more source

Internal deletion mutants ofXenopustranscription factor IIIA

, 1989
Jay S. Hanas, Roanna M. Littell, Chris J. Gaskins, Robert Zebrowski   +3 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Ferroptosis regulation by Cap'n'collar family transcription factors. [PDF]

J Biol Chem
Murray MB, Dixon SJ.
europepmc   +1 more source

Crosslinking of transcription factor TFIIIA to ribosomal 5S RNA fromX.laevisbytrans-diamminedichloroplatinum (II)

, 1989
Florence Baudin, Pascale Romby, Paul J. Romaniuk, Bernard Ehresmann, Chantal Ehresmann   +4 more
openalex   +2 more sources

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Epigenetic regulation of transcription factors involved in NLRP3 inflammasome and NF-kB signaling pathways. [PDF]

Front Immunol
Kaszycki J, Kim M.
europepmc   +1 more source

Roles of Post-Translational Modifications of Transcription Factors Involved in Breast Cancer Hypoxia. [PDF]

Molecules
Seymour L, Nuru N, Johnson KR, Gutierrez JMV, Njoku VT, Darie CC, Neagu AN.   +6 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source