Results 281 to 290 of about 1,348,561 (316)
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Transcription factors in hematopoiesis
Current Opinion in Genetics & Development, 1999The advent of gene targeting in the mouse has led to rapid advances in the identification of factors controlling gene expression that are essential for normal hematopoietic development. Recent work has also uncovered roles for some of these factors in leukemogenesis and in the global regulation of chromatin structure.
Cornelis Murre, Isaac Engel
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Current Opinion in Cell Biology, 1993
Studies of yeast transcription factors have contributed greatly to understanding basic molecular mechanisms of eukaryotic gene regulation, largely due to powerful genetic approaches that are unavailable in other organisms. The broad outlines of these mechanisms are fairly well understood, and there is an increasing number of examples where detailed ...
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Studies of yeast transcription factors have contributed greatly to understanding basic molecular mechanisms of eukaryotic gene regulation, largely due to powerful genetic approaches that are unavailable in other organisms. The broad outlines of these mechanisms are fairly well understood, and there is an increasing number of examples where detailed ...
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Transcription factors on the move
Trends in Genetics, 2001We think of transcription factors as being confined to the cell where they are transcribed, but recent work shows they are able to move from cell to cell in plants. Plant cells are thought to communicate through membrane-lined channels called plasmodesmata.
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Current Opinion in Genetics & Development, 2003
The functions of the basal transcription factors involved in RNA polymerase II dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for ...
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The functions of the basal transcription factors involved in RNA polymerase II dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for ...
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Eukaryotic transcription factors
Current Opinion in Structural Biology, 2002Recently determined high-resolution structures of eukaryotic transcription factors have illuminated the enzymatic mechanism underlying transcription. Progress has been made in characterising protein-protein interactions between negative cofactors and general transcription factors, and between transrepression domains and corepressors.
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Inhibitory transcription factors
The International Journal of Biochemistry & Cell Biology, 1996Although the majority of the transcription factors that were initially characterized had a stimulatory effect on gene expression, it is now clear that transcription factors that inhibit gene transcription are at least as important in regulating a wide variety of processes, including development.
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Roles of transposable elements in the regulation of mammalian transcription
Nature Reviews Molecular Cell Biology, 2022Julius Judd+2 more
exaly