Results 91 to 100 of about 2,065,027 (229)

Stochastic equations for a self-regulating gene [PDF]

, 2014
Expression of cellular genes is regulated by binding of transcription factors to their promoter, either activating or inhibiting transcription of a gene. Particularly interesting is the case when the expressed protein regulates its own transcription.
Jansen, Martin
core   +1 more source

Transcription factor DREF regulates expression of the microRNA gene bantam in Drosophila melanogaster

Вавиловский журнал генетики и селекции
The bantam gene encodes a vital microRNA and has a complex expression pattern in various tissues at different stages of Drosophila development. This microRNA is involved in the control of normal development of the ocu lar and wing imaginal discs, the ...
M. B.  Schwartz, M. M. Prudnikova, O. V. Andreenkov, E. I. Volkova, I. F. Zhimulev, O. V. Antonenko, S.  A. Demakov   +6 more
doaj   +1 more source

Regulation of Topoisomerase IIa expression in humans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2006
In mammalian cells, the loss or down-regulation of tumour-suppressor genes and/or the mutation or overexpression of proto-oncogenes, whose products promote unregulated proliferation in cells, characterise the process of malignant transformation.
Senior, Kelly
core  

New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis

Frontiers in Plant Science, 2019
As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang, Likai Wang, Hong Qiao, Hong Qiao   +3 more
doaj   +1 more source

Chromatin Regulation of HSV Gene Transcription

Viruses
Herpes simplex virus (HSV) has a complicated life cycle including stages of primary lytic infection, latent infection, and reactivation. Although the HSV genomic DNA within the viral capsid is devoid of histones, it rapidly associates with histones upon ...
Yuxuan Zheng, Juncheng Zhang, Dongli Pan
doaj   +1 more source

Author Correction: Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits [PDF]

, 2022
David Salisbury, David Casero, Zhengyi Zhang, Dan Wang, Jason Kim, Xiaohui Wu, Laurent Vergnes, Aashiq H. Mirza, Paola León‐Mimila, Kevin J. Williams, Adriana Huertas‐Vázquez, Samie R. Jaffrey, Karen Reue, Jianjun Chen, Tamer Sallam   +14 more
openalex   +1 more source

The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2

eLife, 2019
RNA polymerase (Pol) I is a 14-subunit enzyme that solely transcribes pre-ribosomal RNA. Cryo-electron microscopy (EM) structures of Pol I initiation and elongation complexes have given first insights into the molecular mechanisms of Pol I transcription.
Lucas Tafur, Yashar Sadian, Jonas Hanske, Rene Wetzel, Felix Weis, Christoph W Müller   +5 more
doaj   +1 more source

Alternative polyadenylation couples to transcription initiation: Insights from ELAV-mediated 3' UTR extension

, 2015
Transcription initiation and mRNA maturation were long considered co-occurring but separately regulated events of gene control. In the past decade, gene promoters, the platforms of transcription initiation, have been assigned additional functions such as
Hilgers, V.
core   +1 more source

Transcriptional Regulation of icaADBC by both IcaR and TcaR in Staphylococcus epidermidis [PDF]

, 2019
Tra-My N. Hoang, Chunyi Zhou, Jill K. Lindgren, Madeline R. Galac, Brendan W. Corey, Jasmin Endres, Merle S. Olson, Paul D. Fey   +7 more
openalex   +1 more source

Identification and Functional Characterization of a Novel SOX4 Mutation Predisposing to Coffin–Siris Syndromic Congenital Heart Disease

Children
Background/Objectives: Congenital heart disease (CHD) occurs in ~1% of all live neonates globally, rendering it the most prevalent developmental anomaly affecting humans; this condition confers substantial infant morbidity and mortality worldwide ...
Zi Yan, Bin-Bin Dong, Yan-Jie Li, Chen-Xi Yang, Ying-Jia Xu, Ri-Tai Huang, Xing-Yuan Liu, Yi-Qing Yang   +7 more
doaj   +1 more source