Results 231 to 240 of about 4,117,946 (252)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Ribosome Profiling and RNA Sequencing Reveal Translation and Transcription Regulation under Acute Heat Stress in Rainbow Trout (Oncorhynchus mykiss, Walbaum, 1792) Liver. [PDF]

Int J Mol Sci
Zhao G, Liu Z, Quan J, Lu J, Li L, Pan Y.   +5 more
europepmc   +1 more source

From promoter motif to cardiac function: a single DPE motif affects transcription regulation and organ function in vivo.

Development
Sloutskin A, Itzhak D, Vogler G, Pozeilov H, Ideses D, Alter H, Adato O, Shachar H, Doniger T, Shohat-Ophir G, Frasch M, Bodmer R, Duttke SH, Juven-Gershon T.   +13 more
europepmc   +1 more source

Transcription regulation by the Mediator complex

Nature Reviews Molecular Cell Biology, 2017
International audienceAlterations in the regulation of gene expression are frequently associated with developmental diseases or cancer. Transcription activation is a key phenomenon in the regulation of gene expression.
Julie Soutourina
exaly   +2 more sources

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Roles of transposable elements in the regulation of mammalian transcription

Nature Reviews Molecular Cell Biology, 2022
Julius A Judd, Joanna Wysocka, Cédric Feschotte   +2 more
exaly  

Mechanisms and regulation of human mitochondrial transcription

Nature Reviews Molecular Cell Biology, 2023
Maria Falkenberg, Claes M. Gustafsson
exaly  

Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes

Nature Reviews Molecular Cell Biology, 2023
Christoph Engel, Yutaro Hori, Takehiko Kobayashi   +2 more
exaly  

Coordinated Transcriptional Regulation by the UV-B Photoreceptor and Multiple Transcription Factors for Plant UV-B Responses

Molecular Plant, 2020
Xinhao Ouyang, Xi Huang, Chongzhen Qian
exaly  

“Structure”-function relationships in eukaryotic transcription factors: The role of intrinsically disordered regions in gene regulation

Molecular Cell, 2022
John Ferrie, Robert Tjian, Xavier Darzacq   +2 more
exaly