Results 281 to 290 of about 5,538,535 (384)

Nanoscale nuclear environments, fine-scale 3D genome organization and transcription regulation. [PDF]

Curr Opin Syst Biol, 2022
Li J, Pertsinidis A.
europepmc   +1 more source

Polypeptide hormone regulation of gene expression. Thyrotropin-releasing hormone rapidly stimulates both transcription of the prolactin gene and the phosphorylation of a specific nuclear protein.

, 1983
Geoffrey Murdoch, Rodrigo Franco, Ronald M. Evans, M G Rosenfeld   +3 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Mutational Analysis Supports Three-Hairpin Model of Attenuator for Transcription Regulation of ilvBNC Operon in Corynebacterium glutamicum. [PDF]

Microorganisms
Ryabchenko LE, Titov II, Leonova TE, Kalinina TI, Gerasimova TV, Sheremetieva ME, Kolchanov NA, Khlebodarova TM, Yanenko AS.   +8 more
europepmc   +1 more source

Transcriptional regulation of a pair-rule stripe in Drosophila. [PDF]

, 1991
Scott A. Small, Rachel Kraut, Timothy Hoey, Rahul Warrior, Michael Levine   +4 more
openalex   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

The role of M2 proteins of pneumoviruses in transcription regulation, prevention of hypermutation, and activation of the type I interferon pathway. [PDF]

J Virol
Ribó-Molina P, Groen K, Susma B, van Nieuwkoop S, Funk M, Fouchier RAM, van den Hoogen BG.   +6 more
europepmc   +1 more source

GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. [PDF]

, 1994
A L Wu, W. Scott Moye‐Rowley
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Proteomic insights into circadian transcription regulation: novel E-box interactors revealed by proximity labeling. [PDF]

Genes Dev
Torres M, Kirchner M, Marks CG, Mertins P, Kramer A.   +4 more
europepmc   +1 more source