Results 221 to 230 of about 744,337 (267)

The AraC transcriptional activators

Current Opinion in Microbiology, 2001
The AraC family of bacterial transcriptional activators regulate diverse genetic systems. Recent X-ray diffraction studies show that the monomeric MarA and Rob activators bind to their asymmetric degenerate DNA sites via two different helix-turn-helix elements.
R G, Martin, J L, Rosner
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Activating Transcription in Bacteria

Annual Review of Microbiology, 2012
Bacteria use a variety of mechanisms to direct RNA polymerase to specific promoters in order to activate transcription in response to growth signals or environmental cues. Activation can be due to factors that interact at specific promoters, thereby increasing transcription directed by these promoters.
David J, Lee, Stephen D, Minchin, Stephen J W, Busby   +2 more
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Cytokine Activation of Transcription

2006
In this review we have attempted to outline the events leading to cytokine-mediated gene transcription by using that Jak/STAT and theNF-kB pathways as two examples. It is important to remember that cytokine activation of gene transcription is not the result of a single, linear signaling cascade, but involves a complex network of interacting signal ...
K A, Mowen, M, David
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Paths to Activation of Transcription

Science, 1997
In bacteria, transcription—the synthesis of RNA from DNA—is carried out by the enzyme RNA polymerase, which binds to the start site of a gene, the promoter. Now two reports in this week's issue, Wyman (p. 1658 ) and Miller (p.
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A Basal Transcription Factor That Activates or Represses Transcription

Science, 2000
We have identified an activity that is required for transcription of downstream promoter element (DPE)–containing core promoters in vitro. The purified factor was found to be the Drosophila homolog of the transcriptional repressor known as NC2 or Dr1-Drap1.
P J, Willy, R, Kobayashi, J T, Kadonaga
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Screening of transcription factors with transcriptional initiation activity

Gene, 2013
A majority of mammalian promoters are associated with CpG islands. CpG island promoters frequently lack common core promoter elements, such as the TATA box, and often have dispersed transcription start sites. The mechanism through which CpG island promoters are transcriptionally initiated remains unclear.
Lang, Zhang, Haoyue, Yu, Pan, Wang, Qingyang, Ding, Zhao, Wang   +4 more
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A brain-specific transcription activator

Neuron, 1989
We have identified a DNA binding protein, named BETA, that interacts with the same (B) transcriptional regulatory sequence as the known transcription factor NF-kappa B. BETA is found only in gray matter throughout the brain, and not in a variety of other rat tissues.
M, Korner, A, Rattner, F, Mauxion, R, Sen, Y, Citri   +4 more
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Transcriptional Activation of APETALA1 by LEAFY

Science, 1999
Plants produce new appendages reiteratively from groups of stem cells called shoot apical meristems. LEAFY (LFY) and APETALA1 (AP1) are pivotal for the switch to the reproductive phase, where instead of leaves the shoot apical meristem produces flowers. Use of steroid-inducible activation of LFY demonstrated that early expression of
Wagner, Doris, Sablowski, Robert W. M., Meyerowitz, Elliot M.   +2 more
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Transcriptional Characteristics of Activated Macrophages

Current Pharmaceutical Design, 2019
Macrophages are key players in human innate immunity that protect the organism from pathologic agents, including infection and malignant cells. The spectrum of their functions includes initiation and maintaining of inflammation, cleaning of pathogens and cell debris, as well as inflammation resolution and tissue remodeling and repair.
Victor, Glanz, Veronika A, Myasoedova, Vasily, Sukhorukov, Andrey, Grechko, Dongwei, Zhang, Elena B, Romaneneko, Varvara A, Orekhova, Alexander, Orekhov   +7 more
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Engineering Vibrio fischeri transcriptional activator LuxR for diverse transcriptional activities

Biotechnology Letters, 2016
To alter DNA binding specificity of Vibrio fischeri LuxR and to expand the toolbox for constructing synthetic networks.A mutation library (about 10,000 individuals) of the DNA binding domain of LuxR were generated. A genetic selection was performed to obtain LuxR mutants that recognize three lux box DNA variants that are not recognized by wild-type ...
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