Results 271 to 280 of about 962,811 (315)

Actin in transcription and transcription regulation

Current Opinion in Cell Biology, 2006
Recent research has provided convincing evidence that actin plays several important roles in gene transcription. First, actin can bind transcription factors and determine their subcellular localization. Second, actin is a component of chromatin remodeling complexes involved in transcriptional activation.
Francesc, Miralles, Neus, Visa
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Transcriptional Regulation and Pharmacogenomics

Pharmacogenomics, 2011
Interindividual variable drug response is correlated with sequence alterations in genes encoding drug-metabolizing enzymes and transporters, affecting drug absorption, distribution, metabolism and excretion. This variable drug response may have an impact on disease therapeutic outcomes, tolerance to adverse drug reactions and even survival.
Georgitsi, Marianthi, Zukić, Branka, Pavlović, Sonja, Patrinos, George P.   +3 more
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Transcriptional regulation of hemopoiesis

Developmental & Comparative Immunology, 2001
The regulation of blood cell formation, or hemopoiesis, is central to the replenishment of mature effector cells of innate and acquired immune responses. These cells fulfil specific roles in the host defense against invading pathogens, and in the maintenance of homeostasis.
D R, Barreda, M, Belosevic
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DnaA as a Transcription Regulator

2003
Publisher Summary This chapter reviews that DnaA is a transcription factor involved in the regulation of several E. Coli genes. DnaA can act as a repressor or it can be a transcriptional activator. DnaA might terminate transcription, provided two suitably located DnaA boxes mediate loop formation of the template.
Messer, W., Weigel, C.
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Transcriptional Regulation of Metabolism

Physiological Reviews, 2006
Our understanding of metabolism is undergoing a dramatic shift. Indeed, the efforts made towards elucidating the mechanisms controlling the major regulatory pathways are now being rewarded. At the molecular level, the crucial role of transcription factors is particularly well-illustrated by the link between alterations of their functions and the ...
Desvergne B, Michalik L, Wahli W
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Transcription Regulation in Spermatogenesis

2009
Spermatogenesis is a highly coordinated process in which diploid spermatogonia (2n) differentiate into mature haploid (1n) spermatozoa in the seminiferous epithelium. In this process, spermatogonia undergo several mitotic divisions and either enter a stem cell renewal pathway, or commit themsevles for further development.
Lui, WY, Cheng, CY
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Mediator of transcriptional regulation

Trends in Biochemical Sciences, 1996
A multi-protein complex, termed mediator, has been isolated from yeast, based on its requirement for transcriptional activation in a system reconstituted from pure RNA polymerase II and general transcription factors. Mediator polypeptides include the products of many genes previously recovered from screens for mutations affecting transcription.
S, Björklund, Y J, Kim
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Transcriptional Regulation of Adipogenesis

Comprehensive Physiology, 2017
ABSTRACT Adipocytes are the defining cell type of adipose tissue. Once considered a passive participant in energy storage, adipose tissue is now recognized as a dynamic organ that contributes to several important physiological processes, such as lipid metabolism, systemic energy homeostasis, and whole‐body insulin
Paula, Mota de Sá, Allison J, Richard, Hardy, Hang, Jacqueline M, Stephens   +3 more
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Mechanogenetic regulation of transcription

Biochimie, 1991
In many biological systems mechanical forces regulate gene expression: in bacteria changes in turgor pressure cause a deformation of the membrane and induce the expression of osmoregulatory genes; in plants gravity regulates cell growth ('geotropism'); in mammals stretching a muscle induces hypertrophy which is accompanied by qualitative changes in ...
T, Erdos, G S, Butler-Browne, L, Rappaport   +2 more
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Transcriptional regulation and metabolism

Biochemical Society Transactions, 2005
Understanding organisms from a systems perspective is essential for predicting cellular behaviour as well as designing gene-metabolic circuits for novel functions. The structure, dynamics and interactions of cellular networks are all vital components of systems biology.
M P, Brynildsen, W W, Wong, J C, Liao
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