Results 281 to 290 of about 1,361,196 (350)

Configuring the Code: Enhancer-Promoter Arrangement and Transcriptional Regulation. [PDF]

J Mol Biol
Buitrago N, Vidal JA, Lim B.
europepmc   +1 more source

Nardilysin controls intestinal tumorigenesis through HDAC1/p53–dependent transcriptional regulation.（研究論文の紹介）

英一郎 西
openalex   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Unveiling ZNF124 as a novel determinant in neurodegeneration: orchestration of photoreceptor homeostasis through MSX2 transcriptional regulation. [PDF]

Cell Death Dis
Yang Y, Jiang X, Li S, Sun K, Zou R, Chen C, Shi Y, Liu W, Sundaresan P, Huang L, Zhang L, Yang Z, Zhu X.   +12 more
europepmc   +1 more source

Copper-responsive transcriptional regulation in Candida albicans

, 2007
Alexandra Woodacre
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking. [PDF]

Sci Adv
Eagle AL, Sugimoto C, Doyle MA, Anderson D, Mousavi SL, Dykstra MM, Kuhn HM, Murray BR, Bastle RM, Simmons S, He J, Maze I, Mazei-Robison MS, Robison AJ.   +13 more
europepmc   +1 more source

Data from: Transcriptional regulation of human NMNAT2: Insights from 3D genome sequencing and bioinformatics

Chang, Yu Chen, Yang, Sen, Cho, Minyoung, Nho, Kwangsik, Baizabal, José-Manuel, Lu, Hui-Chen   +5 more
openalex   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source