Results 111 to 120 of about 602,244 (307)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Transcriptome-guided MiMICS improved prediction accuracy of heterogeneous intracellular metabolism in PA14 biofilm compared to transcriptome-free MiMICS.

From experimental data, plotted is the average percentage of total cells expressing a gene. From transcriptome-guided MiMICS and transcriptome-free MiMICS simulation data, plotted are the average percentage of total agents with active flux through the ...
Mohammad Mazharul Islam (1819852), Tracy J. Kuper (18452180), Shayn M. Peirce-Cottler (12254549), Jason A. Papin (8721624), Roseanne M Ford (18452183)   +4 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Transcriptome-wide identification of microRNAs and functional insights inferred from microRNA—target pairs in Physalis angulata L

, 2019
Physalis angulata L., a member of the family Solanaceae, is widely used as the folk medicine in various countries. Continuous research efforts are devoted to the discovery of the effective medicinal ingredients from Physalis angulata. However, due to the
Dongliang Yu (514041), Huizhong Wang (115600), Yijun Meng (115585), Jiangjie Lu (334945), Min Xu (15203), Jiahui Cai (6693179)   +5 more
core   +1 more source

Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtii [PDF]

, 2011
Toepel J, Albaum S, Arvidsson S, et al. Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtii. BMC Genomics. 2011;12(1): 579.ABSTRACT: BACKGROUND: Chlamydomonas reinhardtii is widely accepted as a model organism regarding ...
La Russa, Marco, Goesmann, Alexander ; https://orcid.org/, Arvidsson, S., Toepel, Jörg, Goesmann, A., Samuel Arvidsson, La Russa, M., Marco la Russa, Kristin Rogge, Toepel Jörg, Albaum, S. P., Rogge Kristin, Alexander Goesmann, Albaum, Stefan ; https://orcid.org/, Kruse, Olaf ; https://orcid.org/, Olaf Kruse, Jörg Toepel, Arvidsson Samuel, Rogge, K., Goesmann Alexander, Albaum Stefan P, Toepel, J., Stefan P Albaum, Kruse Olaf, la Russa Marco, Albaum, S., Rogge, Kristin, Kruse, O.   +27 more
core   +2 more sources

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Transcriptome

, 2018
Fasta file with all contig ...
Barbara Feldmeyer (3242292), Philip Kohlmeier (3293766), Romain Libbrecht (446435), Austin R Alleman (6034817), Susanne Foitzik (176176)   +4 more
core   +1 more source

Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii [PDF]

, 2010
Schmid J, Müller-Hagen D, Bekel T, et al. Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii. BMC Genomics.
Jochen Schmid, Stahl, Ulf, Volker Sieber, Ulf Stahl, Funk, Laura, Müller-Hagen, Dirk, Sieber Volker, Thomas Bekel, Bekel, Thomas, Laura Funk, Schmid, Jochen, Bekel Thomas, Funk Laura, Müller-Hagen Dirk, Schmid Jochen, Meyer, Vera, Dirk Müller-Hagen, Vera Meyer, Stahl Ulf, Meyer Vera, Sieber, Volker   +20 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source