Results 171 to 180 of about 426,916 (271)
Transcriptome Complexity Disentangled: A Regulatory Molecules Approach. [PDF]
Asiaee A, Abrams ZB, Pua HH, Coombes KR.
europepmc +1 more source
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng+11 more
wiley +1 more source
Correction: Use of the Puccinia sorghi haustorial transcriptome to identify and characterize AvrRp1-D recognized by the maize Rp1-D resistance protein. [PDF]
PLOS Pathogens Staff.
europepmc +1 more source
HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou+7 more
wiley +1 more source
Molecular heterogeneity in human stroke - What can we learn from the peripheral blood transcriptome? [PDF]
Stamova B, Knepp B, Rodriguez F.
europepmc +1 more source
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source
Increasing H2B Monoubiquitination Improves the Transcriptome and Memory in the Aged Hippocampus. [PDF]
Kincaid S+7 more
europepmc +1 more source