Results 21 to 30 of about 928,042 (281)
Stem Cell Reports, 2014 A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue.
Mayumi Sugiura +8 more
doaj +1 more source
Fruit fly phylogeny imprints bacterial gut microbiota
Evolutionary Applications, 2022 One promising avenue for reconciling the goals of crop production and ecosystem preservation consists in the manipulation of beneficial biotic interactions, such as between insects and microbes.
Virginie Ravigné +6 more
doaj +1 more source
The Embryonic Transcriptome Of The Red-Eared Slider Turtle (Trachemys Scripta) [PDF]
, 2013 The bony shell of the turtle is an evolutionary novelty not found in any other group of animals, however, research into its formation has suggested that it has evolved through modification of conserved developmental mechanisms.
Cebra-Thomas, J. +14 more
core +2 more sources
Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data
Nature Biotechnology, 2011 Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes. Current approaches for transcript reconstruction from such data often rely on aligning reads to a reference genome, and are thus unsuitable for samples with a
M. Grabherr +20 more
semanticscholar +1 more source
Advancing transcriptome platforms [PDF]
, 2011 During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core +2 more sources
PLOS Computational Biology, 2017 © 2017 Lowe et al. Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription.
Rohan Lowe +4 more
openaire +6 more sources
Oomycete transcriptomics database: A resource for oomycete transcriptomes [PDF]
BMC Genomics, 2012 Oomycete pathogens have attracted significant attention in recent years due to their economic impact. With improving sequencing technologies, large amounts of oomycete transcriptomics data are now available which have great biological utility. A known bottleneck with next generation sequencing data however lies with their analysis, interpretation ...
Brett M. Tyler +3 more
openaire +4 more sources
Human mast cell activation through Fc receptors and Toll-like receptors
Allergology International, 2004 Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE.
Yoshimichi Okayama +7 more
doaj +1 more source
Simultaneous profiling of transcriptome and DNA methylome from a single cell. [PDF]
, 2016 BackgroundSingle-cell transcriptome and single-cell methylome technologies have become powerful tools to study RNA and DNA methylation profiles of single cells at a genome-wide scale. A major challenge has been to understand the direct correlation of DNA
An, Qin +9 more
core +3 more sources
And Now, Transcriptomics [PDF]
Neuron, 2002 In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims.
openaire +3 more sources