Results 21 to 30 of about 426,916 (271)
BMC Genomics, 2018 Background The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus ...
Evelyne Krin +12 more
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TROM: A Testing-based Method for Finding Transcriptomic Similarity of Biological Samples [PDF]
Statistics in Biosciences 9 (2017) 105-136, 2016 Comparative transcriptomics has gained increasing popularity in genomic research thanks to the development of high-throughput technologies including microarray and next-generation RNA sequencing that have generated numerous transcriptomic data. An important question is to understand the conservation and differentiation of biological processes in ...
arxiv +1 more source
The Redox Homeostasis of Skeletal Muscle Cells Regulates Stage Differentiation of Toxoplasma gondii
Frontiers in Cellular and Infection Microbiology, 2021 Toxoplasma gondii is an obligatory intracellular parasite that causes persistent infections in birds and mammals including ~30% of the world’s human population.
Md. Taibur Rahman +8 more
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Comparative analysis of viral RNA signatures on different RIG-I-like receptors
eLife, 2016 The RIG-I-like receptors (RLRs) play a major role in sensing RNA virus infection to initiate and modulate antiviral immunity. They interact with particular viral RNAs, most of them being still unknown.
Raul Y Sanchez David +10 more
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Viruses, 2021 The spread of SARS-CoV-2 and the resulting disease COVID-19 has killed over 2.6 million people as of 18 March 2021. We have used a modified susceptible, infected, recovered (SIR) epidemiological model to predict how the spread of the virus in regions of ...
Chloé Dimeglio +10 more
doaj +1 more source
SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements [PDF]
BMC Genetics 2007 8:78, 2008 Background: Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts into the exon, leading to a new transcript. Several examples in the literature show that isoforms generated by an exonization are specific to a certain ...
arxiv +1 more source
Comparison between the amount of environmental change and the amount of transcriptome change [PDF]
, 2015 Cells must coordinate adjustments in genome expression to accommodate changes in their environment. We hypothesized that the amount of transcriptome change is proportional to the amount of environmental change. To capture the effects of environmental changes on the transcriptome, we compared transcriptome diversities (defined as the Shannon entropy of ...
arxiv +1 more source
Cellular liberality is measurable as Lempel-Ziv complexity of fastq files [PDF]
arXiv, 2022 Many studies used the Shannon entropy of transcriptome data to determine cell dedifferentiation and differentiation. The collection of evidence has strengthened the certainty that the transcriptome's Shannon entropy may be used to quantify cellular dedifferentiation and differentiation.
arxiv
Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae
BMC Biology, 2020 Background In fast-growing bacteria, the genomic location of ribosomal protein (RP) genes is biased towards the replication origin (oriC). This trait allows optimizing their expression during exponential phase since oriC neighboring regions are in higher
Alfonso Soler-Bistué +11 more
doaj +1 more source
The Intestinal Microbiota Interferes with the microRNA Response upon Oral
mBio, 2013 The intestinal tract is the largest reservoir of microbes in the human body. The intestinal microbiota is thought to be able to modulate alterations of the gut induced by enteropathogens, thereby maintaining homeostasis.
Cristel Archambaud +8 more
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