Results 31 to 40 of about 963,153 (378)
Advancing transcriptome platforms [PDF]
, 2011 During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core +2 more sources
Journal of Neuroscience, 2014 The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang +16 more
semanticscholar +1 more source
Stem Cell Reports, 2014 A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue.
Mayumi Sugiura +8 more
doaj +1 more source
Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring
Journal of Fungi, 2021 Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion +11 more
doaj +1 more source
Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data
Nature Biotechnology, 2011 Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes. Current approaches for transcript reconstruction from such data often rely on aligning reads to a reference genome, and are thus unsuitable for samples with a
M. Grabherr +20 more
semanticscholar +1 more source
Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment [PDF]
, 2003 Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric ...
Butcher, PD +10 more
core +3 more sources
PLOS Computational Biology, 2017 © 2017 Lowe et al. Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription.
Rohan Lowe +4 more
openaire +6 more sources
Oomycete transcriptomics database: A resource for oomycete transcriptomes [PDF]
BMC Genomics, 2012 Oomycete pathogens have attracted significant attention in recent years due to their economic impact. With improving sequencing technologies, large amounts of oomycete transcriptomics data are now available which have great biological utility. A known bottleneck with next generation sequencing data however lies with their analysis, interpretation ...
Brett M. Tyler +3 more
openaire +4 more sources
Human mast cell activation through Fc receptors and Toll-like receptors
Allergology International, 2004 Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE.
Yoshimichi Okayama +7 more
doaj +1 more source