Results 31 to 40 of about 450,406 (197)
Bayesian transcriptome assembly [PDF]
Genome Biology, 2014 AbstractRNA sequencing allows for simultaneous transcript discovery and quantification, but reconstructing complete transcripts from such data remains difficult. Here, we introduce Bayesembler, a novel probabilistic method for transcriptome assembly built on a Bayesian model of the RNA sequencing process.
Sørensen, Lasse Maretty +2 more
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High-throughput transcriptomics
Scientific Reports, 2022 High-throughput transcriptomics has revolutionised the field of transcriptome research by offering a cost-effective and powerful screening tool. Standard bulk RNA sequencing (RNA-Seq) enables characterisation of the average expression profiles for individual samples and facilitates identification of the molecular functions associated with genes ...
Nunzio D’Agostino +2 more
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Microorganisms, 2023 In Ruminiclostridium cellulolyticum, cellobiose is imported by the CuaABC ATP-binding cassette transporter containing the solute-binding protein (SBP) CuaA and is further degraded in the cytosol by the cellobiose phosphorylase CbpA.
Aurélie Fosses +7 more
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Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene
BMC Genomics, 2020 Background Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases.
Daniela Kajihara +9 more
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Transcriptomics in toxicology [PDF]
Food and Chemical Toxicology, 2017 Xenobiotics, of which many are toxic, may enter the human body through multiple routes. Excessive human exposure to xenobiotics may exceed the body's capacity to defend against the xenobiotic-induced toxicity and result in potentially fatal adverse health effects.
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BMC Genomics, 2018 Background The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus ...
Evelyne Krin +12 more
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The Redox Homeostasis of Skeletal Muscle Cells Regulates Stage Differentiation of Toxoplasma gondii
Frontiers in Cellular and Infection Microbiology, 2021 Toxoplasma gondii is an obligatory intracellular parasite that causes persistent infections in birds and mammals including ~30% of the world’s human population.
Md. Taibur Rahman +8 more
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Imaging the transcriptome [PDF]
Molecular Systems Biology, 2013 Mol Syst Biol. 9: 710 It is well known that genetically identical cells can display a high variability in their gene expression profiles. This phenomenon has a profound impact on a myriad of cellular processes, ranging from differentiation to signaling and drug resistance.
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Viruses, 2021 The spread of SARS-CoV-2 and the resulting disease COVID-19 has killed over 2.6 million people as of 18 March 2021. We have used a modified susceptible, infected, recovered (SIR) epidemiological model to predict how the spread of the virus in regions of ...
Chloé Dimeglio +10 more
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Comparative transcriptomics in the Triticeae [PDF]
BMC Genomics, 2009 Barley and particularly wheat are two grass species of immense agricultural importance. In spite of polyploidization events within the latter, studies have shown that genotypically and phenotypically these species are very closely related and, indeed, fertile hybrids can be created by interbreeding.
Schreiber, Andreas W. +11 more
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