Results 31 to 40 of about 928,042 (281)
The transcriptome of metamorphosing flatfish [PDF]
BMC Genomics, 2016 Flatfish metamorphosis denotes the extraordinary transformation of a symmetric pelagic larva into an asymmetric benthic juvenile. Metamorphosis in vertebrates is driven by thyroid hormones (THs), but how they orchestrate the cellular, morphological and functional modifications associated with maturation to juvenile/adult states in flatfish is an enigma.
Melody S. Clark +10 more
openaire +6 more sources
BAT: Bisulfite Analysis Toolkit [version 1; referees: 2 approved]
F1000Research, 2017 Here, we present BAT, a modular bisulfite analysis toolkit, that facilitates the analysis of bisulfite sequencing data. It covers the essential analysis steps of read alignment, quality control, extraction of methylation information, and calling of ...
Helene Kretzmer +2 more
doaj +1 more source
Comparison of five different RNA sources to examine the lactating bovine mammary gland transcriptome using RNA-Sequencing. [PDF]
, 2014 The objective of this study was to examine five different sources of RNA, namely mammary gland tissue (MGT), milk somatic cells (SC), laser microdissected mammary epithelial cells (LCMEC), milk fat globules (MFG) and antibody-captured milk mammary ...
Bevilacqua, Claudia +10 more
core +4 more sources
Nature Genetics, 2022 Microglia have emerged as important players in brain aging and pathology. To understand how genetic risk for neurological and psychiatric disorders is related to microglial function, large transcriptome studies are essential.
Katia de Paiva Lopes +19 more
semanticscholar +1 more source
Defining the nociceptor transcriptome [PDF]
Frontiers in Molecular Neuroscience, 2014 Unbiased "omics" techniques, such as next generation RNA-sequencing, can provide entirely novel insights into biological systems. However, cellular heterogeneity presents a significant barrier to analysis and interpretation of these datasets.
Thakur, Matthew +9 more
openaire +5 more sources
Gene Regulation and Transcriptomics [PDF]
Current Issues in Molecular Biology, 2021 Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition from a vertebrate host to a tick vector and transmission from a tick vector to a vertebrate host.
Samuels, D. Scott +8 more
openaire +3 more sources
Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment [PDF]
, 2003 Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric ...
Butcher, PD +10 more
core +3 more sources
Evolution of the unspliced transcriptome [PDF]
BMC Evolutionary Biology, 2015 Despite their abundance, unspliced EST data have received little attention as a source of information on non-coding RNAs. Very little is know, therefore, about the genomic distribution of unspliced non-coding transcripts and their relationship with the much better studied regularly spliced products. In particular, their evolution has remained virtually
Engelhardt, Jan, Stadler, Peter F.
openaire +5 more sources
Transcriptome assembly from long-read RNA-seq alignments with StringTie2
Genome Biology, 2019 RNA sequencing using the latest single-molecule sequencing instruments produces reads that are thousands of nucleotides long. The ability to assemble these long reads can greatly improve the sensitivity of long-read analyses.
S. Kovaka +5 more
semanticscholar +1 more source
Assessing the Gene Content of the Megagenome: Sugar Pine (Pinus lambertiana). [PDF]
, 2016 Sugar pine (Pinus lambertiana Douglas) is within the subgenus Strobus with an estimated genome size of 31 Gbp. Transcriptomic resources are of particular interest in conifers due to the challenges presented in their megagenomes for gene identification ...
Delfino-Mix, Annette +8 more
core +2 more sources