Results 171 to 180 of about 654,399 (276)

MicroRNA transcriptome analysis reveals the potential role of miRNAs in regulating adipocyte hyperplasia and hypertrophy. [PDF]

Front Genet
Ni L, Gu Z, Wang X, Zhang J, Zhou C, Zhang Y, Gao H, Xu P.   +7 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

TIN: An R Package for Transcriptome Instability Analysis

Cancer Informatics, 2015
Bjarne Johannessen, Anita Sveen, Rolf I. Skotheim   +2 more
doaj  

Brain transcriptome analysis reveals novel long non-coding RNAs in Dryophytes arenicolor (Canyon Treefrog). [PDF]

G3 (Bethesda)
Herrera-Orozco H, Rodríguez-Ibarra C, Hernández-Herrera CI, Díaz-Velásquez CE, Vaca-Paniagua F, Pérez-Mendoza HA.   +5 more
europepmc   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Chromosome-level genome assembly and transcriptome analysis of the Ural owl, Strix uralensis Pallas, 1771. [PDF]

J Hered
Winter S, Meißner R, Grethlein M, Wehrenberg G, Kiebler A, Silva AX, Escobar NR, Quesada Calderón SM, Suescún AV, Belmar LG, Prost S.   +10 more
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Integrated metabolome and transcriptome analysis provides insights into anthocyanin biosynthesis in Portulaca oleracea. [PDF]

BMC Plant Biol
Zhu M, Wu H, Fu Y, You L, Yang C, Zhao R, Han X.   +6 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Methcathinone Neurotoxicity in the Rat Prefrontal Cortex by Integrated Synaptic Changes and Transcriptome Analysis. [PDF]

Addict Biol
Zhou R, Xu Y, Xu C, Chen Z, Lv J, Yun K, Wei Z.   +6 more
europepmc   +1 more source