Results 231 to 240 of about 660,896 (300)

Transcriptome analysis of differentially expressed genes in lily leaves under selenite application. [PDF]

Sci Rep
Yang Y, Duan Y, Li D, Jiang X, Wang H, Liu H, Zhang M, You J, Zhou W.   +8 more
europepmc   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Comprehensive androgen-dependent transcriptome analysis in human genital tissue. [PDF]

BMC Genomics
Sivaprasad R, Händler K, Caliebe A, Spielmann M, Holterhus PM, Hornig NC.   +5 more
europepmc   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source

Transcriptome analysis reveals KRAS as a crucial regulator of ovarian follicle development in Wuding chickens. [PDF]

BMC Genomics
Zhu W, Fan X, Han C, Teng X, Miao Y.
europepmc   +1 more source

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, EarlyView.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Transcriptome Analysis Provides New Insight into Apoptosis and Immunosuppression in <i>Procambarus clarkii</i> After Exposure to High Temperature. [PDF]

Biology (Basel)
Ren S, Xu W, Ma X, Gui Q, Tian W, Liu Q, Dai L, Bian D.   +7 more
europepmc   +1 more source

Transcriptome analysis of hormone-related genes in winter rapeseed treated by different photoperiods and vernalization times. [PDF]

BMC Plant Biol
Ren S, Gong H, Ma Y, Zhang L, Li X, Pu Y, Ma L, Liu L, Wang W, Yang G, Fan T, Sun W, Wu J.   +12 more
europepmc   +1 more source