Comparative transcriptome, digital gene expression and proteome profiling analyses provide insights into the brachyurization from the megalopa to the first juvenile in Eriocheir sinensis. [PDF]
Yang Y +7 more
europepmc +1 more source
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources [PDF]
Background: Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown. The increasing amount of microarray data for many species allows employing the guilt-by-association principle to predict ...
Hofstede, K.J. +27 more
core +1 more source
Transcriptome-Wide Gene Expression Plasticity in Stipa grandis in Response to Grazing Intensity Differences. [PDF]
Dang Z +9 more
europepmc +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Improved robustness in time series analysis of gene expression data by polynomial model based clustering [PDF]
Microarray experiments produce large data sets that often contain noise and considerable missing data. Typical clustering methods such as hierarchical clustering or partitional algorithms can often be adversely affected by such data.
Liu, X +20 more
core +1 more source
Bridging Synaptic and Epigenetic Maintenance Mechanisms of the Engram
How memories are maintained, and how memories are lost during aging or disease, are intensely investigated issues. Arguably, the reigning theory is that synaptic modifications allow for the formation of engrams during learning, and sustaining engrams ...
Madeleine Kyrke-Smith +3 more
doaj +1 more source
Transcriptome-wide Gene Expression Analysis in Peri-implantitis Reveals Candidate Cellular Pathways. [PDF]
Martin A, Zhou P, Singh BB, Kotsakis GA.
europepmc +1 more source
Underground Signals: The Ecological Power of Root Volatiles
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao +31 more
wiley +1 more source
A robust Bayesian two-sample test for detecting intervals of differential gene expression in microarray time series [PDF]
Understanding the regulatory mechanisms that are responsible for an organism's response to environmental change is an important issue in molecular biology.
Cooke, Emma J. +18 more
core +1 more source

