Results 121 to 130 of about 7,548,191 (313)

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources [PDF]

open access: yes, 2008
Background: Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown. The increasing amount of microarray data for many species allows employing the guilt-by-association principle to predict ...
Hofstede, K.J.   +27 more
core   +1 more source

Transcriptome-Wide Gene Expression Plasticity in Stipa grandis in Response to Grazing Intensity Differences. [PDF]

open access: yesInt J Mol Sci, 2021
Dang Z   +9 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Improved robustness in time series analysis of gene expression data by polynomial model based clustering [PDF]

open access: yes, 2006
Microarray experiments produce large data sets that often contain noise and considerable missing data. Typical clustering methods such as hierarchical clustering or partitional algorithms can often be adversely affected by such data.
Liu, X   +20 more
core   +1 more source

Bridging Synaptic and Epigenetic Maintenance Mechanisms of the Engram

open access: yesFrontiers in Molecular Neuroscience, 2018
How memories are maintained, and how memories are lost during aging or disease, are intensely investigated issues. Arguably, the reigning theory is that synaptic modifications allow for the formation of engrams during learning, and sustaining engrams ...
Madeleine Kyrke-Smith   +3 more
doaj   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

open access: yesAdvanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao   +31 more
wiley   +1 more source

A robust Bayesian two-sample test for detecting intervals of differential gene expression in microarray time series [PDF]

open access: yes, 2010
Understanding the regulatory mechanisms that are responsible for an organism's response to environmental change is an important issue in molecular biology.
Cooke, Emma J.   +18 more
core   +1 more source

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