Results 31 to 40 of about 499,194 (265)

Transcriptome approach to understand the potential mechanisms of resistant and susceptible alfalfa (Medicago sativa L.) cultivars in response to aphid feeding

Journal of Integrative Agriculture, 2018
Plant breeding for resistance to agricultural pests is an essential element in the development of integrated crop management systems, however, the molecular and genetic mechanisms underlying resistance are poorly understood.
Xiong-bing TU, Hai-long ZHAO, Ze-hua ZHANG   +2 more
doaj   +1 more source

Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions [PDF]

, 2019
Fungal infections, ranging from superficial to life-threatening infections, represent a major public health problem that affects 25% of the worldwide population.
Coucke, Paul, Guillemyn, Brecht, Rodriguez Sánchez, Antonio, Vaneechoutte, Mario   +3 more
core   +1 more source

Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]

, 2017
The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul, Gomez-Pinilla, Fernando, Meng, Qingying, Yang, Xia, Ying, Zhe, Zhuang, Yumei   +5 more
core   +2 more sources

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]

, 2010
Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex, Altschul, Anja Joachim, Ashburner, Bentley, Bethony, Björnberg, Blaxter, Boag, Bronwyn E. Campbell, Caffrey, Campbell, Cantacessi, Cantacessi, Cantacessi, Cantacessi, Chan, Chang, Cinzia Cantacessi, Clifton, Conesa, Cottee, Cottee, Datu, DeRisi, Doyle, Flicek, Freigofas, Gasser, Golden, Greene, Gupta, Hawdon, Hopkins, Hotez, Hu, Huang, Hunter, Iseli, Jackson, Joachim, Joachim, Keil, Krasky, Letunic, Li, Li, Li, Lipinski, Makedonka Mitreva, Margulies, Matthew J. Nolan, McKay, Metzker, Miller, Miller, Mizuarai, Moreno, Morozova, Moser, Mufson, Mulvenna, Nagaraj, Nagaraj, Neil D. Young, Nikolaou, Nisbet, Olson, Parkinson, Paul W. Sternberg, Pong, Portman, Ranganathan, Ren, Robertson, Robin B. Gasser, Robinson, Ross S. Hall, Sahar Abubucker, Sanger, Sanger, Santos, Shoba Ranganathan, Soderlund, Stathopoulos, Stockdale, Tanaka, Vibranovski, Wang, Williamson, Wilson, Wu, Young, Young, Zhan, Zhong   +95 more
core   +6 more sources

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]

, 2019
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn, Burgess, Stewart TG, Down, Rachel E, Dunn, Jackie, Marr, Edward J, Nisbet, Alasdair J, Nunn, Francesca G, Prickett, Jessica C, Rombauts, Stephane, Van de Peer, Yves, Van Leeuwen, Thomas, Weaver, Robert J   +11 more
core   +2 more sources

Fungal Transcriptomics

, 2018
Transcriptomics, the study of RNA molecules, provides in-depth understanding of cellular functions and the genomic landscape of transcription. Transcriptomics refers to the study of all classes on RNA molecules including mRNA, tRNA, and siRNA. In this chapter, we specifically focus on mRNA, which encodes the protein-coding portion of the genomic DNA ...
Singan, Vasanth R, Kuo, Rita C, Chen, Cindy   +2 more
openaire   +4 more sources

A comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta

Frontiers in Genetics, 2022
Background: The etiology of preeclampsia (PE) remains unclear. With the utilization of metabolomics, dysregulated production of several metabolic components in human plasma, such as lipids, amino acids, androgens and estrogens, was found to be important ...
Yan Feng, Xinlei Lian, Kaimin Guo, Guanglan Zhang, Xuan Huang   +4 more
doaj   +1 more source

Transcriptomic and Immunopathological Profiles of Inflammasomes in Different Clinical Forms of American Cutaneous Leishmaniasis

Microorganisms
American cutaneous leishmaniasis (ACL), caused by Leishmania (Leishmania) amazonensis and L. (Viannia) braziliensis, presents a wide spectrum of clinical and immunopathological manifestations, ranging from localized cutaneous leishmaniasis (LCL) to ...
Larissa dos Santos Alcântara, Marliane Batista Campos, Ana Carolina Stocco Lima, Alessandra Pontillo, Kamilla Batista da Silva Souza, Aurea Favero Ferreira, Cristina Pires Camargo, Sueli Mieko Oba-Shinjo, Márcia Dalastra Laurenti, Carlos Eduardo Pereira Corbett, Vania L. R. da Matta, Helder Nakaya, Fernando T. Silveira, Claudia Maria de Castro Gomes   +13 more
doaj   +1 more source

Transcriptional and translational differences of microglia from male and female brains [PDF]

, 2019
Sex differences in brain structure and function are of substantial scientific interest because of sex-related susceptibility to psychiatric and neurological disorders. Neuroinflammation is a common denominator of many of these diseases and thus microglia
Güneykaya, Dilansu
core   +1 more source

Integrated Transcriptomic Analysis of Liver and Muscle Tissues Reveals Candidate Genes and Pathways Regulating Intramuscular Fat Deposition in Beef Cattle

Animals
Intramuscular fat (IMF) content in beef cattle is a critical determinant of beef meat quality, as it positively influences juiciness, tenderness, and palatability.
Siwei Wang, Tingting Liu, Peng Peng, Yurong Fu, Shaoqing Shi, Shuang Liang, Xi Chen, Kun Wang, Rongyan Zhou   +8 more
doaj   +1 more source