Results 1 to 10 of about 479,279 (168)

Proteomic Methods of Detection and Quantification of Protein Toxins

open access: yesToxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Alena Fučíková   +2 more
exaly   +3 more sources

Plasma proteomic associations with genetics and health in the UK Biobank

open access: yesNature, 2023
The Pharma Proteomics Project generates the largest open-access plasma proteomics dataset to date, offering insights into trans protein quantitative trait loci across multiple biological domains, and highlighting genetic influences on ligand–receptor ...
Benjamin B. Sun   +55 more
semanticscholar   +1 more source

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations

open access: yesNature Medicine, 2023
Circulating plasma proteins play key roles in human health and can potentially be used to measure biological age, allowing risk prediction for age-related diseases, multimorbidity and mortality.
M. Argentieri   +23 more
semanticscholar   +1 more source

Consolidation of metabolomic, proteomic, and GWAS data in connective model of schizophrenia

open access: yesScientific Reports, 2023
Despite of multiple systematic studies of schizophrenia based on proteomics, metabolomics, and genome-wide significant loci, reconstruction of underlying mechanism is still a challenging task. Combination of the advanced data for quantitative proteomics,
Arthur T. Kopylov   +7 more
doaj   +1 more source

Proteomic characterization and biological activities of the mucus produced by the zoanthid Palythoa caribaeorum (Duchassaing & Michelotti, 1860) [PDF]

open access: yesAnais da Academia Brasileira de Ciências, 2023
Mucus, produced by Palythoa caribaeorum has been popularly reported due to healing, anti-inflammatory, and analgesic effects. However, biochemical and pharmacological properties of this mucus remains unexplored.
MARLLYN M. SILVA   +7 more
doaj   +1 more source

Noninvasive proteomic biomarkers for alcohol-related liver disease

open access: yesNature Medicine, 2022
Alcohol-related liver disease (ALD) is a major cause of liver-related death worldwide, yet understanding of the three key pathological features of the disease—fibrosis, inflammation and steatosis—remains incomplete. Here, we present a paired liver–plasma
L. Niu   +15 more
semanticscholar   +1 more source

Network Topological Analysis for the Identification of Novel Hubs in Plant Nutrition

open access: yesFrontiers in Plant Science, 2021
Network analysis is a systems biology-oriented approach based on graph theory that has been recently adopted in various fields of life sciences. Starting from mitochondrial proteomes purified from roots of Cucumis sativus plants grown under single or ...
Dario Di Silvestre   +5 more
doaj   +1 more source

Proteomic and Metabolomic Characterization of COVID-19 Patient Sera

open access: yesmedRxiv, 2020
Severe COVID-19 patients account for most of the mortality of this disease. Early detection and effective treatment of severe patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control
B. Shen   +39 more
semanticscholar   +1 more source

Pan-cancer proteomic map of 949 human cell lines

open access: yesbioRxiv, 2022
The proteome provides unique insights into biology and disease beyond the genome and transcriptome. Lack of large proteomic datasets has restricted identification of new cancer biomarkers.
E. Gonçalves   +31 more
semanticscholar   +1 more source

Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery

open access: yesMolecular Neurodegeneration, 2021
Mass spectrometry-based proteomics empowers deep profiling of proteome and protein posttranslational modifications (PTMs) in Alzheimer’s disease (AD). Here we review the advances and limitations in historic and recent AD proteomic research. Complementary
B. Bai   +9 more
semanticscholar   +1 more source

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