Results 21 to 30 of about 591,485 (302)
Proteomic interrogation of human chromatin. [PDF]
, 2011 Chromatin proteins provide a scaffold for DNA packaging and a basis for epigenetic regulation and genomic maintenance. Despite understanding its functional roles, mapping the chromatin proteome (i.e. the "Chromatome") is still a continuing process. Here,
LeRoy, Gary +22 more
core +2 more sources
BMC Nephrology, 2017 Background Additional urinary biomarkers for diabetic nephropathy (DN) are needed, providing early and reliable diagnosis and new insights into its mechanisms.
Lenka Vitova +5 more
doaj +1 more source
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
Nature reviews genetics, 2012 Recent advances in next-generation DNA sequencing and proteomics provide an unprecedented ability to survey mRNA and protein abundances. Such proteome-wide surveys are illuminating the extent to which different aspects of gene expression help to regulate
C. Vogel, E. Marcotte
semanticscholar +1 more source
Pooling serum samples may lead to loss of potential biomarkers in SELDI-ToF MS proteomic profiling. [PDF]
, 2008 BACKGROUND: High throughput proteomic technology offers promise for the detection of disease biomarkers and proteomic signature patterns but biomarker discovery studies can be limited by cost factors when large sample size numbers are required.
Dan Agranoff +5 more
core +1 more source
A proteomic atlas of senescence-associated secretomes for aging biomarker development
bioRxiv, 2019 The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of, and promising therapeutic target for, multiple age-related conditions, ranging from neurodegeneration to cancer. The complexity of the SASP, typically assessed by a
N. Basisty +11 more
semanticscholar +1 more source
Proteomic profiles of cultured cells stimulated with VEGFs dimers and search for natural compounds angiogenesis inhibitors [PDF]
, 2013 2010 - 2011Some members of the vascular endothelial growth factor (VEGF) family, such as VEGF and PlGF, and related receptors (KDR and Flt-1) play a key role in the modulation of angiogenesis, both physiological and pathological. For this reason they are
Pesca, Mariasabina
core +1 more source
Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
Frontiers in Microbiology, 2018 Antimicrobial peptides are sequences of amino acids, which present activity against microorganisms. These peptides were discovered over 70 years ago, and are abundant in nature from soil bacteria, insects, amphibians to mammals and plants.
Lubhandwa S. Biswaro +7 more
doaj +1 more source
Frontiers in Immunology, 2021 The COVID-19 pandemic caused by SARS-CoV-2 challenges the understanding of factors affecting disease progression and severity. The identification of prognostic biomarkers and physiological processes associated with disease symptoms is relevant for the ...
Margarita Villar +13 more
doaj +1 more source
Data on genome analysis of Mycoplasma gallisepticum during intracellular infection
Data in Brief, 2017 The genus Mycoplasma relates to Gram-positive bacteria that lack a cell wall and are capable to cause chronic disease in humans and animals. Among the agents of infection and disease in domestic poultry and wild birds, Mycoplasma gallisepticum is the ...
Daria Matyushkina +6 more
doaj +1 more source
Click Chemistry in Proteomic Investigations
Cell, 2020 Despite advances in genetic and proteomic techniques, a complete portrait of the proteome and its complement of dynamic interactions and modifications remains a lofty, and as of yet unrealized objective.
Christopher G. Parker, Matthew R. Pratt
semanticscholar +1 more source