Results 21 to 30 of about 599,323 (353)

Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles: a combined targeted and proteomic approach [PDF]

, 2014
Two different zinc oxide nanoparticles, as well as zinc ions, are used to study the cellular responses of the RAW 264 macrophage cell line. A proteomic screen is used to provide a wide view of the molecular effects of zinc, and the most prominent results
Armand, Lucie, Aude-Garcia, Catherine, Carrière, Marie, Collin-Faure, Véronique, Diemer, Hélène, Gerdil, Adèle, Habert, Aurélie, Hanau, Daniel, Herlin, Nathalie, Proamer, Fabienne, Rabilloud, Thierry, Strub, Jean-Marc, Triboulet, Sarah, Van Dorsselaer, Alain   +13 more
core   +4 more sources

Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines

Journal of Immunology Research, 2016
Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium.
Petr G. Lokhov, Elena E. Balashova
doaj   +1 more source

The Effect of Neurotoxin MPTP and Neuroprotector Isatin on the Profile of Ubiquitinated Brain Mitochondrial Proteins

Cells, 2018
Mitochondria are a crucial target for the actions of neurotoxins, causing symptoms of Parkinson’s disease in various experimental animal models, and also neuroprotectors.
Olga Buneeva, Arthur Kopylov, Inga Kapitsa, Elena Ivanova, Victor Zgoda, Alexei Medvedev   +5 more
doaj   +1 more source

Differential Proteomic Expression of Equine Cardiac and Lamellar Tissue During Insulin-Induced Laminitis

Frontiers in Veterinary Science, 2020
Endocrinopathic laminitis is pathologically similar to the multi-organ dysfunction and peripheral neuropathy found in human patients with metabolic syndrome.
Allison Campolo, Matthew W. Frantz, Melody A. de Laat, Melody A. de Laat, Steven D. Hartson, Martin O. Furr, Véronique A. Lacombe   +6 more
doaj   +1 more source

Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]

, 2016
Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core   +2 more sources

Multiple short windows of calcium-dependent protein kinase 4 activity coordinate distinct cell cycle events during Plasmodium gametogenesis

eLife, 2017
Malaria transmission relies on the production of gametes following ingestion by a mosquito. Here, we show that Ca2+-dependent protein kinase 4 controls three processes essential to progress from a single haploid microgametocyte to the release of eight ...
Hanwei Fang, Natacha Klages, Bastien Baechler, Evelyn Hillner, Lu Yu, Mercedes Pardo, Jyoti Choudhary, Mathieu Brochet   +7 more
doaj   +1 more source

Profiling plasma‐extracellular vesicle proteins and microRNAs in diabetes onset in middle‐aged male participants in the ELSA‐Brasil study

Physiological Reports, 2021
We measured plasma‐derived extracellular vesicle (EV) proteins and their microRNA (miRNA) cargos in normoglycemic (NG), glucose intolerant (GI), and newly diagnosed diabetes mellitus (DM) in middle‐aged male participants of the Brazilian Longitudinal ...
Laureane N. Masi, Paulo A. Lotufo, Frederico M. Ferreira, Alice C. Rodrigues, Tamires D. A. Serdan, Talita Souza‐Siqueira, Aécio A. Braga, Magda E. G. Saldarriaga, Tatiana C. Alba‐Loureiro, Fernanda T. Borges, Diego P. Cury, Mario H. Hirata, Renata Gorjão, Tania C. Pithon‐Curi, Simão A. Lottenberg, Ligia M. G. Fedeli, Helder T. I. Nakaya, Isabela J. M. Bensenor, Rui Curi, Sandro M. Hirabara   +19 more
doaj   +1 more source

Proteomic and metabolomic analysis of Nicotiana benthamiana under dark stress

FEBS Open Bio, 2022
Exposure to extended periods of darkness is a common source of abiotic stress that significantly affects plant growth and development. To understand how Nicotiana benthamiana responds to dark stress, the proteomes and metabolomes of leaves treated with ...
Juan‐Juan Shen, Qian‐Si Chen, Ze‐Feng Li, Qing‐Xia Zheng, Ya‐Long Xu, Hui‐Na Zhou, Hong‐Yan Mao, Qi Shen, Ping‐Ping Liu   +8 more
doaj   +1 more source

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia [PDF]

, 2015
In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal ...
Agulla, Jesús, Blanco, Miguel, Brea, David, Campos, Francisco, Castillo, José, Dávalos, Antoni, Gevaert, Kris, Ramos-Cabrer, Pedro, Sobrino, Tomás, Staes, An   +9 more
core   +5 more sources

Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation : a tale of the unexpected [PDF]

, 2020
ObjectiveTo assess the clinical, radiologic, myopathologic, and proteomic findings in a patient manifesting a multisystem proteinopathy due to a homozygous valosin-containing protein gene (VCP) mutation previously reported to be pathogenic in the ...
Azmi, A, Baets, J, Clemen, CS, De Bleecker, Jan, De Jonghe, P, De Ridder, W, Eichinger, L, Hofmann, A, Johnson, K, Maudsley, S, Schröder, R, Straub, V, Töpf, A   +12 more
core   +1 more source