Results 11 to 20 of about 383,189 (303)

Development and evaluation of statistical approaches in proteomic biomarker discovery [PDF]

open access: yes, 2011
A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or pharmacological responses to a therapeutic intervention.
Patel, Amit
core   +5 more sources

Pooling serum samples may lead to loss of potential biomarkers in SELDI-ToF MS proteomic profiling. [PDF]

open access: yes, 2008
BACKGROUND: High throughput proteomic technology offers promise for the detection of disease biomarkers and proteomic signature patterns but biomarker discovery studies can be limited by cost factors when large sample size numbers are required.
Dan Agranoff   +5 more
core   +1 more source

Proteomic interrogation of human chromatin. [PDF]

open access: yes, 2011
Chromatin proteins provide a scaffold for DNA packaging and a basis for epigenetic regulation and genomic maintenance. Despite understanding its functional roles, mapping the chromatin proteome (i.e. the "Chromatome") is still a continuing process. Here,
LeRoy, Gary   +30 more
core   +2 more sources

Nanotechnologies in Proteomics [PDF]

open access: yesChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yuri D, Ivanov   +3 more
openaire   +2 more sources

Proteomic analysis for the study of amniotic fluid protein composition [PDF]

open access: yes, 2009
Amniotic fluid (AF), routinely used for prenatal diagnosis, contains large amounts of proteins produced by the amnion epithelial cells, fetal tissues, fetal excretions and placental tissues. Although many amniotic fluid proteins have been identified and
Giorlandino, Claudio   +8 more
core   +1 more source

Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines

open access: yesJournal of Immunology Research, 2016
Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium.
Petr G. Lokhov, Elena E. Balashova
doaj   +1 more source

The Effect of Neurotoxin MPTP and Neuroprotector Isatin on the Profile of Ubiquitinated Brain Mitochondrial Proteins

open access: yesCells, 2018
Mitochondria are a crucial target for the actions of neurotoxins, causing symptoms of Parkinson’s disease in various experimental animal models, and also neuroprotectors.
Olga Buneeva   +5 more
doaj   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

open access: yes, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Owen, Christopher B   +14 more
core   +1 more source

Multiple short windows of calcium-dependent protein kinase 4 activity coordinate distinct cell cycle events during Plasmodium gametogenesis

open access: yeseLife, 2017
Malaria transmission relies on the production of gametes following ingestion by a mosquito. Here, we show that Ca2+-dependent protein kinase 4 controls three processes essential to progress from a single haploid microgametocyte to the release of eight ...
Hanwei Fang   +7 more
doaj   +1 more source

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