Results 51 to 60 of about 449,144 (306)

Cross-species analysis of abiotic stress in hydroponic leafy crops reveals conserved regulatory networks and key divergences

Frontiers in Plant Science
Hydroponics is emerging as a vital method for producing resilient leafy greens in controlled environments. To systematically capture how hydroponically grown crops respond to stress, we subjected three species—cai xin, lettuce, and spinach—to 24 ...
Jia Min Lee, Jia Min Lee, Jong Ching Goh, Eugene Koh, Daniela Mutwil-Anderwald, Marek Mutwil, Marek Mutwil   +6 more
doaj   +1 more source

Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper

Biomedicines, 2020
Feae’s viper Azemipos feae belongs to the Azemiopinae subfamily of the Viperidae family. The effects of Viperidae venoms are mostly coagulopathic with limited neurotoxicity manifested by phospholipases A2. From A.
Vladislav V. Babenko, Rustam H. Ziganshin, Christoph Weise, Igor Dyachenko, Elvira Shaykhutdinova, Arkady N. Murashev, Maxim Zhmak, Vladislav Starkov, Anh Ngoc Hoang, Victor Tsetlin, Yuri Utkin   +10 more
doaj   +1 more source

Integrated transcriptomic and metabolic analyses provide insights into the maintenance of embryogenic potential and the biosynthesis of phenolic acids and flavonoids involving transcription factors in Larix kaempferi (Lamb.) Carr.

Frontiers in Plant Science, 2022
Somatic embryogenesis (SE) techniques have been established for micropropagation or basic research related to plant development in many conifer species.
Junchen Wang, Junchen Wang, Lifeng Zhang, Lifeng Zhang, Liwang Qi, Liwang Qi, Shougong Zhang, Shougong Zhang   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Transcriptomic response analyses.

, 2020
Transcriptomic response analyses.
Irina N. Shilova (8735340), Matthew M. Mills (8735346), Kendra A. Turk-Kubo (8735352), Jonathan D. Magasin (8735343), Julie C. Robidart (8735349), Jonathan P. Zehr (8735355)   +5 more
core   +1 more source

Approaching the holistic transcriptome—convolution and deconvolution in transcriptomics

Briefings in Bioinformatics
Abstract Tissues, organs, and entire organisms are composed of diverse cell populations, which are characterized by cell-type-specific gene activities. Bulk RNA-seq represents a robust, cost-effective, scalable method to measure gene activity at the bulk tissue level.
Maik Wolfram-Schauerte, Thomas Vogel, Hanati Tuoken, Maria Fälth Savitski, Eric Simon, Kay Nieselt   +5 more
openaire   +3 more sources

Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes

Cells
Human-induced pluripotent stem cell (iPSC)-derived hepatocyte-like cells (HLCs) have been shown to be useful for the development of cell-based regenerative strategies and for modelling drug discovery.
Saqlain Suleman, Sharmin Alhaque, Andrew Guo, Aaron Zhang, Serena Fawaz, Stefany Perera, Mohammad S. Khalifa, Hassan Rashidi, David C. Hay, Michael Themis   +9 more
doaj   +1 more source

Integrated Excitatory/Inhibitory Imbalance and Transcriptomic Analysis Reveals the Association between Dysregulated Synaptic Genes and Anesthetic-Induced Cognitive Dysfunction

Cells, 2022
Emerging evidence from human epidemiologic and animal studies has demonstrated that developmental anesthesia neurotoxicity could cause long-term cognitive deficits and behavioral problems. However, the underlying mechanisms remain largely unknown.
Yasheng Yan, Sarah Logan, Xiaojie Liu, Bixuan Chen, Congshan Jiang, Thiago Arzua, Ramani Ramchandran, Qing-song Liu, Xiaowen Bai   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Transcriptomic signatures

, 2023
Two transcriptomic signatures that I derived for Chapter 2 of my thesis using RNA-seq data from a xenograft model of breast cancer progression. This work is associated with a published manuscript (DOI: 10.1126/sciadv.abf4408) and the data is publicly ...
Holly Whitfield (6602102)
core   +1 more source