Results 71 to 80 of about 449,144 (306)

Multi-omics analysis reveals the molecular changes accompanying heavy-grazing-induced dwarfing of Stipa grandis

Frontiers in Plant Science, 2022
Heavy grazing significantly reduces Stipa grandis growth. To enhance our understanding of plant responses to heavy grazing, we conducted transcriptomic, proteomic, and metabolic analyses of the leaves of non-grazed plants (NG) and heavy-grazing-induced ...
Dongli Wan, Yongqing Wan, Tongrui Zhang, Ruigang Wang, Yong Ding   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential [PDF]

, 2009
J Physiol Pharmacol. 2009 May;60 Suppl 1:95-106. Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential. Krol M, Pawlowski KM, Skierski J, Rao NA, Hellmen E, Mol JA, Motyl T. Department of
Tissue Repair, Geneeskunde van gezelschapsdieren, Krol, M., Skierski, J., Motyl, T., Hellmen, E., Rao, N.A., Mol, J.A.   +7 more
core  

The transcriptome of Toxoplasma gondii

BMC Biology, 2005
AbstractBackgroundToxoplasma gondiigives rise to toxoplasmosis, among the most prevalent parasitic diseases of animals and man. Transformation of the tachzyoite stage into the latent bradyzoite-cyst form underlies chronic disease and leads to a lifetime risk of recrudescence in individuals whose immune system becomes compromised.
Roos David S, Radke Josh B, Mackey Aaron J, Behnke Michael S, Radke Jay R, White Michael W   +5 more
openaire   +3 more sources

Integrating Transcriptomic and Metabolomic Analyses to Explore the Effect of Color Under Fruit Calyx on That of Fruit Apex in Eggplant (Solanum melongena L.)

Frontiers in Genetics, 2022
Fruit color is an important commercial characteristic of eggplant (Solanum melongena L.), which affects both the profits of growers and consumer choice.
Jingjing Zhang, Bing Li, Xiurui Gao, Xiuqing Pan, Yanrong Wu   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Transcriptomic data - C3G & controls (TBM)

, 2023
Transcriptomic data from n= 36 kidney samples from C3 Glomerulopathy patients + n=8 controles (thin basement membrane) 847 genes transcripts studied = PanCancer immune profiling panel = 730 immune related genes + house panel of 117 genes (2 separarated ...
Petitprez, Florent; id_orcid, School of Regeneration and Repair, Centre for Reproductive Health, marie-sophie, meuleman, chauvet, sophie   +4 more
core   +1 more source

Elucidating the Interaction of CF Airway Epithelial Cells and Rhinovirus: Using the Host-Pathogen Relationship to Identify Future Therapeutic Strategies

Frontiers in Pharmacology, 2018
Chronic lung disease remains the primary cause of mortality in cystic fibrosis (CF). Growing evidence suggests respiratory viral infections are often more severe in CF compared to healthy peers and contributes to pulmonary exacerbations (PEx) and ...
Kak-Ming Ling, Kak-Ming Ling, Luke W. Garratt, Timo Lassmann, Stephen M. Stick, Stephen M. Stick, Stephen M. Stick, Stephen M. Stick, Anthony Kicic, Anthony Kicic, Anthony Kicic, Anthony Kicic, Anthony Kicic, WAERP, AusREC, AusREC, AusREC, Australian Respiratory Early Surveillance Team for Cystic Fibrosis, Australian Respiratory Early Surveillance Team for Cystic Fibrosis, Australian Respiratory Early Surveillance Team for Cystic Fibrosis, Australian Respiratory Early Surveillance Team for Cystic Fibrosis   +20 more
doaj   +1 more source

Transcriptomics and metabolomics changes triggered by exogenous 6-benzylaminopurine in relieving epicotyl dormancy of Polygonatum cyrtonema Hua seeds

Frontiers in Plant Science, 2022
Polygonatum cyrtonema Hua is one of the most useful herbs in traditional Chinese medicine and widely used in medicinal and edible perennial plant. However, the seeds have the characteristics of epicotyl dormancy.
Wenwu Zhang, Long Xia, Fulei Peng, Chenyu Song, Muhammad Aamir Manzoor, Yongping Cai, Qing Jin   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source