Results 91 to 100 of about 449,144 (306)
Frontiers in Veterinary ScienceBackgroundControlling gastrointestinal nematode infections poses a major challenge in intensive farming, worsened by rising anthelmintic resistance. Developing innovative control strategies is critical.
Bin Hou +16 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Colorectal cancer (CRC), a complex and molecularly heterogenous disease that lacks robust predictive markers and targeted therapies, is the second leading cause of cancer death worldwide.
Chew, Xiao Hong +19 more
core +1 more source
Transcriptomic genet LRT results and enrichment analyses.
, 2023 Transcriptomic genet LRT results and enrichment analyses.
Amelia Moura (11552319) +7 more
core +1 more source
BiologyGoose foie gras production requires force-feeding with high-energy feed, disrupting hepatic lipid homeostasis and causing excessive lipid accumulation.
Qi Zhang +8 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
A transcriptomic and molecular approach uncovering ASCL2 as a novel tumourigenic gene in breast cancer [PDF]
, 2019 Breast cancer is highly heterogeneous and is considered a collection of molecularly distinct tumour subtypes. Substantial efforts have been made to explore the gene expression profiles underlying the subtypes, and to elucidate possible markers associated
Faramarzi, N.
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Transcriptomic Insights into the Physiological Aspects of the Saprotrophic Fungus Penicillium citrinum During the Spoilage of Tobacco Leaves [PDF]
Penicillium citrinum is one of the most prevalent tobacco spoilage fungi. However, the mechanisms underlying fungal growth on tobacco leaves remain largely unknown.
Qi Li +3 more
core +1 more source
The transcriptomic basis of oviposition behaviour in the parasitoid wasp Nasonia vitripennis [PDF]
, 2013 Linking behavioural phenotypes to their underlying genotypes is crucial for uncovering the mechanisms that underpin behaviour and for understanding the origins and maintenance of genetic variation in behaviour.
Shuker, David M +32 more
core +1 more source