Results 91 to 100 of about 475,601 (307)

Summary of transcriptomic profiling of lymphohematopoietic tissues.

open access: yes, 2014
Summary of transcriptomic profiling of lymphohematopoietic tissues.
Karolina Edlund (262572)   +8 more
core   +1 more source

Genomic and transcriptomic datasets used in this study.

open access: yes, 2023
Genomic and transcriptomic datasets used in this study.
Louise E. Atkinson (9235356)   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptomic contig expression levels

open access: yes, 2016
Expression levels of the transcriptomic contigs based on the alignment of the non-normalised cDNA library sequence reads against the assembled ...
Federico Luebert (3260688)   +7 more
core   +1 more source

Transcriptome and Temporal Transcriptome Analyses in Single Cells

open access: yesInternational Journal of Molecular Sciences
Transcriptome analysis in single cells, enabled by single-cell RNA sequencing, has become a prevalent approach in biomedical research, ranging from investigations of gene regulation to the characterization of tissue organization. Over the past decade, advances in single-cell RNA sequencing technology, including its underlying chemistry, have ...
Jun Lyu, Chongyi Chen
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Seurat object for the spatial transcriptomic data of sample HCM1220B

open access: yes, 2022
Seurat object for the spatial transcriptomic data of sample ...
Xuanyu Liu (5556740)
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

GIANT : Galaxy-based tool for Interactive ANalysis of Transcriptomic data

open access: yes, 2020
International audienceBackground: Transcriptomic analyses are broadly used in biomedical research calling for tools allowing biologists to be directly involved in data mining and interpretation; Results: We present here GIANT, a Galaxy-based tool for ...
Staels, Bart   +5 more
core   +2 more sources

A new view of transcriptome complexity and regulation through the lens of local splicing variations

open access: yeseLife, 2016
Alternative splicing (AS) can critically affect gene function and disease, yet mapping splicing variations remains a challenge. Here, we propose a new approach to define and quantify mRNA splicing in units of local splicing variations (LSVs).
Jorge Vaquero-Garcia   +7 more
doaj   +1 more source

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