Results 121 to 130 of about 320,395 (368)

Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation [PDF]

, 2015
Phytoplankton growth rates are limited by the supply of iron (Fe) in approximately one third of the open ocean, with major implications for carbon dioxide sequestration and carbon (C) biogeochemistry.
Boyd, Philip W., Faux, Jessica F., Goodlett, David R., Harvey, H. Rodger, Hippmann, Anna A., Maldonado, Maria T., Nunn, Brook L., Strzepek, Robert F.   +7 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Evolution: The Plastic Transcriptome [PDF]

Current Biology, 2006
Studies across a wide range of species point to a surprising degree of plasticity in the transcriptional states that organisms can adopt, suggesting that organisms often respond to environmental challenges through wholesale reprogramming of their gene expression.
openaire   +4 more sources

Yeast Mitochondrial Transcriptomics [PDF]

, 2007
Although 30 years ago it was strongly suggested that some cytoplasmic ribosomes are bound to the surface of yeast mitochondria, the mechanisms and the raison d'être of this process are not understood. For instance, it is not perfectly known which of the several hundred nuclearly encoded genes have to be translated to the mitochondrial vicinity to guide
Mathilde Garcia, Frédéric Devaux, Robert H. Singer, Xavier Darzacq, Xavier Darzacq, Claude Jacq   +5 more
openaire   +4 more sources

Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage

Scientific Reports, 2021
In multicellular organisms, oocytes and sperm undergo fusion during fertilization and the resulting zygote gives rise to a new individual. The ability of zygotes to produce a fully formed individual from a single cell when placed in a supportive ...
Marino Maemura, Hiroaki Taketsuru, Yuki Nakajima, Ruiqi Shao, Ayaka Kakihara, Jumpei Nogami, Yasuyuki Ohkawa, Yu-ichi Tsukada   +7 more
doaj   +1 more source

Enabling precision medicine in neonatology, an integrated repository for preterm birth research. [PDF]

, 2018
Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. In the last decade, the advent and continued development of molecular profiling technologies has enabled researchers to ...
Anderson, Rebecca, Banerjee, Payal, Butte, Atul J, Chappell, Joanne, Chubiz, Jessica, England, Sarah K, Grobman, William, Kim, Mara, Leite, Rita, Liu, Rebecca, March of Dimes Prematurity Research Centers, Parry, Samuel, Quaintance, Cecele C, Rokas, Antonis, Shaw, Gary M, Simpson, Joe Leigh, Sirota, Marina, Thomas, Cristel G, Thomson, Elizabeth, Wong, Ronald J, Zhang, Ge, Zuhl, Maya   +21 more
core   +4 more sources

Genomes and Transcriptomes of Duckweeds [PDF]

Frontiers in Chemistry, 2018
Duckweeds (Lemnaceae family) are the smallest flowering plants that adapt to the aquatic environment. They are regarded as the promising sustainable feedstock with the characteristics of high starch storage, fast propagation, and global distribution.
Wenqin Wang, Yongrui Wu, Yong Zhou, Changsheng Li, Dong An   +4 more
openaire   +4 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states

Nature Communications
Cell states are regulated by the response of signaling pathways to receptor ligand-binding and intercellular interactions. High-resolution imaging has been attempted to explore the dynamics of these processes and, recently, multiplexed imaging has ...
Kosuke Tomimatsu, Takeru Fujii, Ryoma Bise, Kazufumi Hosoda, Yosuke Taniguchi, Hiroshi Ochiai, Hiroaki Ohishi, Kanta Ando, Ryoma Minami, Kaori Tanaka, Taro Tachibana, Seiichi Mori, Akihito Harada, Kazumitsu Maehara, Masao Nagasaki, Seiichi Uchida, Hiroshi Kimura, Masashi Narita, Yasuyuki Ohkawa   +18 more
doaj   +1 more source

MTS1338, A Small Mycobacterium tuberculosis RNA, Regulates Transcriptional Shifts Consistent With Bacterial Adaptation for Entering Into Dormancy and Survival Within Host Macrophages

Frontiers in Cellular and Infection Microbiology, 2019
Small non-coding RNAs play a significant role in bacterial adaptation to changing environmental conditions. We investigated the dynamics of expression of MTS1338, a small non-coding RNA of Mycobacterium tuberculosis, in the mouse model in vivo ...
Elena G. Salina, Artem Grigorov, Yulia Skvortsova, Konstantin Majorov, Oksana Bychenko, Albina Ostrik, Nadezhda Logunova, Dmitriy Ignatov, Arseny Kaprelyants, Alexander Apt, Tatyana Azhikina   +10 more
doaj   +1 more source