Results 181 to 190 of about 398,969 (379)

Plasma cell differentiation is regulated by the expression of histone variant H3.3

open access: yesNature Communications
The differentiation of B cells into plasma cells is associated with substantial transcriptional and epigenetic remodeling. H3.3 histone variant marks active chromatin via replication-independent nucleosome assembly.
Yuichi Saito   +10 more
doaj   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Clinical metagenomics. [PDF]

open access: yes, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

MUSTANG: Multi-sample spatial transcriptomics data analysis with cross-sample transcriptional similarity guidance

open access: yesPatterns
Summary: Spatially resolved transcriptomics has revolutionized genome-scale transcriptomic profiling by providing high-resolution characterization of transcriptional patterns.
Seyednami Niyakan   +7 more
doaj   +1 more source

A Reassessment of the FNR Regulon and Transcriptomic Analysis of the Effects of Nitrate, Nitrite, NarXL, and NarQP as Escherichia coli K12 Adapts from Aerobic to Anaerobic Growth [PDF]

open access: hybrid, 2005
Chrystala Constantinidou   +6 more
openalex   +1 more source

RNA-Seq: a revolutionary tool for transcriptomics

open access: yesNature reviews genetics, 2009
Zhong Wang, M. Gerstein, M. Snyder
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy