Results 201 to 210 of about 299,908 (313)

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

So3D: a comprehensive three-dimensional spatial omics resource for decoding tissue architecture in physiology and disease. [PDF]

Nucleic Acids Res
Zhao H, Yin X, Wang S, Geng Z, Yu W, Yu H, Ning S, Wang L.   +7 more
europepmc   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

DeepSpaceDB: a spatial transcriptomics atlas for interactive in-depth analysis of tissues and tissue microenvironments. [PDF]

Nucleic Acids Res
Honcharuk V, Zainab A, Horimoto Y, Takemoto K, Diez D, Kawaoka S, Vandenbon A.   +6 more
europepmc   +1 more source

DeepST: A versatile graph contrastive learning framework for spatially informed clustering, integration and deconvolution of spatial transcriptomics

, 2022
Yahui Long
openalex   +2 more sources

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

A supervised Bayesian method for time (re)annotation of transcriptomics data. [PDF]

NAR Genom Bioinform
Nushi E, Douillard FP, Selby K, Blount BA, Pennington OJ, Minton NP, Lindström M, Honkela A.   +7 more
europepmc   +1 more source

Spatial transcriptomic profiling of metastatic renal cell carcinoma identifies chemokine-driven macrophage and CD8+ T-cell interactions predictive of immunotherapy response [PDF]

Charis Kalogirou, Markus Krebs, Andreas Steven Kunz, Oliver Hahn, Hubert Kübler, Marcel Schwinger, Arndt Hartmann, Astrid Schmieder, Markus Eckstein   +8 more
openalex   +1 more source

Transcriptomic data of bevacizumab-adapted colorectal adenocarcinoma cells HCT-116

, 2023
Cesare Sala, Tiziano Lottini, Elena Lastraioli, Federico Alessandro Ruffinatti, Luca Visentin, Annarosa Arcangeli   +5 more
openalex   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source