Results 231 to 240 of about 248,325 (264)

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu, Xiaoxia Ren, Mi Mu, Huanyu Long, Jialu Lv, Zhihong Feng, Jie Liu, Jiajia Wang, Hui Deng, Fanyu Shi, Muzhi Zhang, Ruoyang Zhang, Yang Liu, Mengyu Xu, Yang Fan, Zengtao Wang, Zhe Lv, Yan Chen, Chris J. Corrigan, Ying Sun, Yahong Chen, Chen Chen, Ye Cui, Wei Wang   +23 more
wiley   +1 more source

moiraine: an R package to construct reproducible pipelines for the application and comparison of multi-omics integration methods. [PDF]

Bioinformatics
Angelin-Bonnet O, Guo L, Storey R, Thomson S.   +3 more
europepmc   +1 more source

Advances in Spatial Transcriptomics in Bone. [PDF]

Curr Osteoporos Rep
Giger NV, Wehrle E.
europepmc   +1 more source

Discovering paracrine regulators of cell type composition from spatial transcriptomics using SPER. [PDF]

Bioinform Adv
Zhao T, Haber AL.
europepmc   +1 more source

So3D: a comprehensive three-dimensional spatial omics resource for decoding tissue architecture in physiology and disease. [PDF]

Nucleic Acids Res
Zhao H, Yin X, Wang S, Geng Z, Yu W, Yu H, Ning S, Wang L.   +7 more
europepmc   +1 more source

HIF2α-induced lysyl oxidase safeguards successful pregnancy by remodelling collagens at the feto-maternal interface. [PDF]

Cell Death Dis
Aikawa S, Shimizu-Hirota R, Sakashita A, He X, Hiratsuka D, Ishizawa C, Iida R, Fukui Y, Hiraoka T, Matsuo M, Takeda N, Ikawa M, Osuga Y, Hirota Y.   +13 more
europepmc   +1 more source

Bridging cancer cell-intrinsic driver genes and -extrinsic cell-cell communication with Driver2Comm. [PDF]

PLoS Comput Biol
Xie R, Li J, Hu Y, Gao L.
europepmc   +1 more source