Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter+5 more
wiley +1 more source
DiSTect: a Bayesian model for disease-associated gene discovery and prediction in spatial transcriptomics. [PDF]
Zhao Q, Deng A, Zhang Q.
europepmc +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
Spatial and single-cell transcriptomics capture two distinct cell states in soybean defense response to <i>Phakopsora pachyrhizi</i> infection. [PDF]
Hu Y+17 more
europepmc +1 more source
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis [PDF]
Robert Kleemann+16 more
openalex +1 more source
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu+9 more
wiley +1 more source
Spatial transcriptomics herald a new era of transcriptome research
Dominik Saul, Robyn Laura Kosinsky
openaire +3 more sources
Glycolysis-Driven Immune Evasion in Microsatellite Instability-High Colorectal Cancer: An Integrated Single-Cell and Spatial Transcriptomics Study. [PDF]
Li C+8 more
europepmc +1 more source