Results 271 to 280 of about 256,508 (379)

m2ST: dual multi-scale graph clustering for spatially resolved transcriptomics. [PDF]

Bioinformatics
Zhang W, Zhang Z, Yang H, Zhang T, Jiang S, Qiao N, Deng Z, Pan X, Shen HB, Yu DJ, Wang S.   +10 more
europepmc   +1 more source

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

A trispeciesAspergillusmicroarray: Comparative transcriptomics of threeAspergillusspecies [PDF]

, 2008
Mikael Rørdam Andersen, Wanwipa Vongsangnak, Gianni Panagiotou, Margarita Salazar, Linda Lehmann, Jens Nielsen   +5 more
openalex   +1 more source

Application of Spatial Omics in the Cardiovascular System. [PDF]

Research (Wash D C)
Hu Y, Jia H, Cui H, Song J.
europepmc   +1 more source

Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Advanced Science, EarlyView.
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan, Xing He, Su Wu, Na Xiong, Xinyu Hou, Heting Wang, Diane Somlo, Martin Spiess, Haiyang Wang, Jifeng Yang, Chunliang Li, Shasha Li, Wenbin Ma, Yanming Chen, Jun Cui, Ling Qi, Guojun Shi   +16 more
wiley   +1 more source

Transcriptomics, Proteomics, and Structural Genomics of Pyrococcus Furiosus

, 2006
Michael W. W. Adams, Francis E. Jenney, Chung‐Jung Chou, Scott D. Hamilton-Brehm, Farris L. Poole, Keith R. Shockley, Sabrina Tachdjian, Robert M. Kelly   +7 more
openalex   +1 more source

Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis Revealed by Proteomic and Transcriptomic Analyses of the Striata in Two Mouse Models of Parkinson’s Disease [PDF]

, 2008
Mark H. Chin, Weijun Qian, Hai Wang, Vladislav Petyuk, Joshua S. Bloom, Daniel M. Sforza, Goran Laćan, Dahai Liu, Arshad H. Khan, Rita M. Cantor, Diana J. Bigelow, William P. Melega, David Camp, Richard Smith, Desmond Smith   +14 more
openalex   +1 more source

Untargeted metabolomics and transcriptomics joint analysis of the effects of polystyrene nanoplastics on lipid metabolism in the mouse liver. [PDF]

Lipids Health Dis
Chen L, Sui G, Wu J, Li N, Zhang Z, Du Y, Lü M, Yan X, Pan G, Jia L.   +9 more
europepmc   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source