This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim+5 more
wiley +1 more source
Spatial transcriptomics meets diabetic kidney disease: Illuminating the path to precision medicine. [PDF]
Liu DD+6 more
europepmc +1 more source
Understanding the bi‐directional crosstalk between cells and their surrounding extracellular matrix (ECM) is critical for tissue engineering. This study presents a chemoselective strategy for proteomic profiling of newly deposited ECM from resident cells.
Zihan Ling+9 more
wiley +1 more source
Correction to "Unveiling the Molecular Mechanisms of Rosacea: Insights From Transcriptomics and In Vitro Experiments". [PDF]
europepmc +1 more source
SpaIM: single-cell spatial transcriptomics imputation via style transfer. [PDF]
Li B+7 more
europepmc +1 more source
Integrated application of transcriptomics, proteomics, and metallomics in environmental studies [PDF]
Macarena González-Fernández+6 more
openalex +1 more source
Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae+6 more
wiley +1 more source
STmiR: A Novel XGBoost-based framework for spatially resolved miRNA activity prediction in cancer transcriptomics. [PDF]
Yuan J, Xu P, Ye Z, Liu W.
europepmc +1 more source
The transcriptomic signature of fasting murine liver [PDF]
Milka Sokolović+9 more
openalex +1 more source
Engineering Aging: Approaches to Model and Deconstruct Biological Complexity
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar+7 more
wiley +1 more source