Results 291 to 300 of about 256,508 (379)

Phenotypic and Transcriptomic Changes Associated With Potato Autopolyploidization

, 2007
Robert M. Stupar, Pudota B. Bhaskar, Brian S. Yandell, Willem Albert Rensink, Amy Hart, Shu Ouyang, Richard E. Veilleux, James S. Busse, Robert J. Erhardt, C. Robin Buell, Jiming Jiang   +10 more
openalex   +1 more source

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

Advanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng   +16 more
wiley   +1 more source

Combined transcriptomics and metabolomics analyses reveal the molecular mechanism of heat tolerance in <i>Pichia kudriavzevii</i>. [PDF]

Front Microbiol
Wang N, Li L, Ma Y, Shen C, Ao Z, Song C, Mehmood MA, Zhang P, Liu Y, Sun X, Zhu H.   +10 more
europepmc   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

Transcriptomic analysis of growth heterosis in larval Pacific oysters ( Crassostrea gigas )

, 2007
Dennis Hedgecock, Jing-Zhong Lin, Shannon Decola, Christian Haudenschild, Eli Meyer, Donal T. Manahan, Ben Bowen   +6 more
openalex   +1 more source

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis [PDF]

, 2019
Cole, M, Gross, CC, Hartlehnert, M, Heming, M, Lautwein, T, Meuth, SG, Schafflick, D, Schulte-Mecklenbeck, A, Wiendl, H, Xu, CA, Yosef, N, zu Hoerste, G Meyer   +11 more
core  

spaMGCN: a graph convolutional network with autoencoder for spatial domain identification using multi-scale adaptation. [PDF]

Genome Biol
Zhang T, Zhang H, Zhao Z, Shao S, Jiang Y, Zhang X, Wang G.   +6 more
europepmc   +1 more source

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Advanced Science, EarlyView.
Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang, Wenqing Xu, Yutian Xiao, Dingheng Su, Yusheng He, Huohong Yang, Yixin Xie, Xiaofang Wang, Ren‐He Xu, Shaorong Lei, Dingyu Wu   +10 more
wiley   +1 more source

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

Advanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang, Ye Zhang, Zhu Liu, Zhiyuan Wang, Huaqin Wang, Xiaoyu Ji, Hongyue Su, Fan Yang, Lirong Yan, Ying Xu, Hao Zhang, Wei Sun   +11 more
wiley   +1 more source

Integrating Dynamical Systems Modeling with Spatiotemporal scRNA-Seq Data Analysis. [PDF]

Entropy (Basel)
Zhang Z, Sun Y, Peng Q, Li T, Zhou P.
europepmc   +1 more source