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Current Drug Metabolism, 2008
Transcriptomics, a genome-wide measurement of mRNA expression levels based on DNA microarray technology is one of the prominent fields of study. This is the term given to the set of all transcripts or messenger RNA (mRNA) molecules produced in cells. It can also be applied to the specific subset of transcripts present in a particular cell or the total ...
Virendra S, Gomase, Somnath, Tagore
+6 more sources
Transcriptomics, a genome-wide measurement of mRNA expression levels based on DNA microarray technology is one of the prominent fields of study. This is the term given to the set of all transcripts or messenger RNA (mRNA) molecules produced in cells. It can also be applied to the specific subset of transcripts present in a particular cell or the total ...
Virendra S, Gomase, Somnath, Tagore
+6 more sources
Cancer Cell, 2022
Spatial transcriptomics, with other spatial technologies, has enabled scientists to dissect the organization and interaction of different cell types within the tumor microenvironment. We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor ...
Ana C, Anderson +12 more
openaire +2 more sources
Spatial transcriptomics, with other spatial technologies, has enabled scientists to dissect the organization and interaction of different cell types within the tumor microenvironment. We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor ...
Ana C, Anderson +12 more
openaire +2 more sources
Expansion Spatial Transcriptomics
Nature Methods, 2022AbstractCapture array-based spatial transcriptomics methods have been widely used to resolve gene expression in diverse tissue contexts, however, their spatial resolution is limited by array density. We present Expansion Spatial Transcriptomics (Ex-ST) to overcome this limitation by clearing and expanding tissue prior to capturing the entire ...
Yuhang Fan +8 more
openaire +2 more sources
2011
Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the production of recombinant proteins, knowledge of the expression conditions of the influencing genes is a major issue in the improvement of cell lines
Frank, Stahl +7 more
openaire +2 more sources
Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the production of recombinant proteins, knowledge of the expression conditions of the influencing genes is a major issue in the improvement of cell lines
Frank, Stahl +7 more
openaire +2 more sources
2017
This chapter focuses on transcriptomes. A transcriptome is the inventory of the RNA molecules in a cell. The chapter differentiates between proteomes and genomes. It explains the relationship between microarray technology and RNAseq methods, including the gene expression table and how it is derived from experiments using these methods. It clarifies the
openaire +2 more sources
This chapter focuses on transcriptomes. A transcriptome is the inventory of the RNA molecules in a cell. The chapter differentiates between proteomes and genomes. It explains the relationship between microarray technology and RNAseq methods, including the gene expression table and how it is derived from experiments using these methods. It clarifies the
openaire +2 more sources