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2011
Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the production of recombinant proteins, knowledge of the expression conditions of the influencing genes is a major issue in the improvement of cell lines
Frank, Stahl+7 more
openaire +2 more sources
Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the production of recombinant proteins, knowledge of the expression conditions of the influencing genes is a major issue in the improvement of cell lines
Frank, Stahl+7 more
openaire +2 more sources
Transcriptomic Analyses of Phytoplasmas
2018Transcriptomic analyses addressed to study phytoplasma gene expression may present few difficulties due to the uncultivable nature of these intracellular, obligate pathogens. While RNA extraction from insect vectors does not imply any particular adaptation of the protocols used in most commercial kits, RNA isolation from phytoplasma-infected plants can
Pacifico D, Abba S, Palmano S
openaire +4 more sources
Transcriptomics on Small Samples
2012Interrogating the cell-specific transcriptome forms an important component of understanding the role that specific cells play in assisting a plant to overcome abiotic stress. Among the challenges arising when extracting RNA from individual plant cells are: the isolation of pure cell populations; the small yield of material when isolating specific cell ...
Roy, S.+4 more
openaire +5 more sources
Exploring tissue architecture using spatial transcriptomics
Nature, 2021Anjali Rao, Dalia Barkley, Itai Yanai
exaly
Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics
Nature Reviews Molecular Cell Biology, 2022Takayuki Nojima, Nick J Proudfoot
exaly
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease
Cell, 2020Wei-ting Chen+2 more
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Single-cell transcriptomics for the assessment of cardiac disease
Nature Reviews Cardiology, 2023Sarah A Teichmann+2 more
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Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics
Nature Reviews Genetics, 2021Margaret G Guo+2 more
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