Results 51 to 60 of about 141,563 (385)

Optimization of Influential Variables in the Development of Buprenorphine and Bupivacaine Loaded Invasome for Dermal Delivery [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: Hydrophilic drugs are extensively applied in clinical applications. Inadequate dermal penetration of these drugs is a great challenge. Incorporation of drugs into nano-carrier systems overcomes lower penetration drawbacks.
Soraya Babaie, Arezou Taghvimi, Mohammad Charkhpour, Amir Zarebkohan, Peyman Keyhanvar, Hamed Hamishehkar   +5 more
doaj   +1 more source

Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? [PDF]

, 2003
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially ...
Alan J. Jaap, Andersen, Anderson, Ann Rumley, Anne Kelly, Brussard, Cushman, Dichtl, Ferrara, Gordon D. Lowe, Gornstein, Herrington, Hokanson, Hulley, Ian A. Greer, John R. Petrie, Joyce McKenzie, Kanaya, Kenneth Paterson, Knopp, Koh, Kroon, Kroon, Lokkegaard, Lowe, Lowe, Lowe, Lynne Crawford, Manning, Meade, Naveed Sattar, Perera, Petitti, Pradhan, Rapp, Ridker, Ridker, Rossouw, Sattar, Sattar, Stephen Gallacher, Stork, Van Baal, Van Baal, Vehkavaara, Woodward, Zanger   +46 more
core   +1 more source

Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review

Archives of Gynecology and Obstetrics, 2022
Purpose To summarize available evidence comparing the transdermal and the oral administration routes of hormone replacement therapy (HRT) in postmenopausal women.
Marina Sprem Goldstajn, M. Mikuš, F. Ferrari, M. Bosco, S. Uccella, M. Noventa, P. Török, S. Terzic, A. Laganà, S. Garzon   +9 more
semanticscholar   +1 more source

Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology

Molecules, 2017
Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it ...
Tyler Pentek, Eric Newenhouse, Brennin O’Brien, Abhay Singh Chauhan   +3 more
doaj   +1 more source

Beyond the pill: New medication delivery options for ADHD [PDF]

, 2017
Successful treatment of pediatric disorders has necessitated the development of alternative medication formulations, as children may prefer alternative dosage forms to tablets or capsules.
Cutler, Andrew J, Mattingly, Gregory W
core   +2 more sources

Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study

INNOVATIONS in Pharmacy
Background: Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates.
Roda Plakogiannis, Abraham Stefanidis, Nubriel Hernandez, Etty Vider   +3 more
doaj   +1 more source

Physiologically-based pharmacokinetic simulations in pharmacotherapy: selection of the optimal administration route for exogenous melatonin

ADMET and DMPK, 2019
The benefits of melatonin on human body are drawing increasing attention from several researchers in different fields. While its role as cure for sleep disturbances (e.g., jet lag, insomnia) is well documented and established, new functions in ...
Adriana Savoca, Davide Manca
doaj   +1 more source

Design, Development, and Evaluation of Treprostinil Embedded Adhesive Transdermal Patch

Pharmaceutics, 2023
Clinical application of treprostinil in pulmonary arterial hypertension is hampered by adverse effects caused by its high dosing frequency. The objective of this investigation was to Formulate an adhesive-type transdermal patch of treprostinil and ...
Ibrahim Alissa, Anroop B. Nair, Bandar Aldhubiab, Hiral Shah, Jigar Shah, Vivek Mewada, Rashed M. Almuqbil, Shery Jacob   +7 more
doaj   +1 more source

Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]

, 2016
Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H, Mattingly, Gregory W   +1 more
core   +2 more sources

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected

Scientia Pharmaceutica, 2020
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden, Jeanetta du Plessis, Joe Viljoen   +2 more
doaj   +1 more source