Results 261 to 270 of about 1,640,128 (340)

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

Dimethylsiloxane polymers for the effective transdermal delivery of Minoxidil in hair loss treatment. [PDF]

Biomed Eng Lett
Kim J, Kim D.
europepmc   +1 more source

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

iNew Medicine, EarlyView.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li, Xu Liu, Xin Ye, Zhixia Dong, Xinjian Wan   +4 more
wiley   +1 more source

Expression of concern: Electrothermal patches driving the transdermal delivery of insulin.

Nanoscale Horiz
Pagneux Q, Ye R, Chengnan L, Barras A, Hennuyer N, Staels B, Caina D, Osses JIA, Abderrahmani A, Plaisance V, Pawlowski V, Boukherroub R, Melinte S, Szunerits S.   +13 more
europepmc   +1 more source

Characteristics of Hydrogels as a Coating for Microneedle Transdermal Delivery Systems with Agomelatine. [PDF]

Molecules
Wojtyłko M, Nowicka AB, Froelich A, Szybowicz M, Banaszek T, Tomczak D, Kuczko W, Wichniarek R, Budnik I, Jadach B, Kordyl O, Białek A, Krysztofiak J, Osmałek T, Lamprou DA.   +14 more
europepmc   +1 more source

Therapeutic Potential of Photobiomodulation in Early Recovery After Experimental Spinal Cord Injury in Rats: Histological and Biomechanical Analysis

Journal of Biophotonics, EarlyView.
Spinal cord injuries (SCI) cause severe motor and sensory deficits, with limited treatment options. This study demonstrates that early application of photobiomodulation (PBM) can protect spinal cord tissue and accelerate functional recovery in a preclinical model, which integrates biomechanical analysis with histomorphological characteristics of the ...
Débora Campos Chaves Correia, Leonardo Borges de Lima, Mário Oliveira Lima, Luis Filipe Karatanasov Beloni, Raduan Hage, Emilia Angela Lo Schiavo Arisawa   +5 more
wiley   +1 more source

Preparation and Evaluation of Tadalafil-Loaded Nanoemulgel for Transdermal Delivery in Cold-Induced Vasoconstriction: A Potential Therapy for Raynaud's Phenomenon. [PDF]

Pharmaceutics
Jacob S, Abdullahi JO, Usman S, Boddu SHS, Khan SN, Saad MA, Nair AB.   +6 more
europepmc   +1 more source

Nanostructured lipid carriers and natural deep eutectic solvents: a highly advantageous combination for the encapsulation of curcumin

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari, Ioanna Pitterou, Marianthi Miliaronikolaki, Nikolaos Paraskevopoulos, Andromachi Tzani, Anastasia Detsi   +5 more
wiley   +1 more source

Diagnosis of Amniotic Sac Herniation Into Uterine Dehiscence Using Combined Ultrasound and Magnetic Resonance Imaging—A Rare Complication Following Fetoscopic Laser Photocoagulation

Journal of Clinical Ultrasound, EarlyView.
Fistula of the anterior uterine wall, through which the amniotic sac of the recipient communicated with the anechoic area outside the uterus (left: ultrasound imaging; right: MRI imaging; star: amniotic sac herniation; arrow: fistula; triangle: bladder).
Ziling Liu, Hongqin Chen, Jie Ruan
wiley   +1 more source

Sialic Acid-Loaded Nanoliposomes with Enhanced Stability and Transdermal Delivery for Synergistic Anti-Aging, Skin Brightening, and Barrier Repair. [PDF]

Pharmaceutics
Yang F, Wang H, Luo D, Deng J, Hu Y, Liu Z, Liu W.   +6 more
europepmc   +1 more source