Results 271 to 280 of about 1,640,128 (340)

Neoadjuvant Chemotherapy With Gemcitabine/Cisplatin/S‐1 for Resectable Biliary Tract Cancer With FDG‐PET‐Positive Lymph Node Metastasis (KHBO1201): A Multicenter Phase II Trial

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Purpose To evaluate the safety and efficacy of neoadjuvant gemcitabine, cisplatin, and S‐1 (GCS) chemotherapy for resectable biliary tract cancer (BTC) and FDG‐PET‐positive lymph nodes in a multicenter phase II study (KHBO1201). Methods Patients with resectable BTC (intrahepatic/extrahepatic bile duct, gallbladder, or ampullary cancers) and ...
Satoshi Ogiso, Etsuro Hatano, Satoru Seo, Masashi Kanai, Shogo Kobayashi, Hiroshi Wada, Hidetoshi Eguchi, Tatsuya Higashi, Hiroaki Nagano, Tatsuya Ioka   +9 more
wiley   +1 more source

A Hierarchical Short Microneedle-Cupping Dual-Amplified Patch Enables Accelerated, Uniform, Pain-Free Transdermal Delivery of Extracellular Vesicles. [PDF]

Nanomicro Lett
Song M, Ha M, Shin S, Kim M, Son S, Lee J, Hwang GW, Kim J, Duong VH, Park JH, Pang C.   +10 more
europepmc   +1 more source

Enhanced transdermal delivery of pioglitazone hydrochloride via conductive hydrogel microneedles combined with iontophoresis. [PDF]

Int J Pharm X
Hu J, An Y, Wang W, Yang J, Niu W, Jiang X, Li K, Jiang C, Ye J.   +8 more
europepmc   +1 more source

Nanocarrier-mediated transdermal delivery of Lmidgf4 dsRNA expedites biological control of locusts by Beauveria bassiana. [PDF]

J Nanobiotechnology
Kong X, Tan S, Guan M, Lin X, Shen J, Shi W, Wang D.   +6 more
europepmc   +1 more source

A double network composite hydrogel with enhanced transdermal delivery by ultrasound for endometrial injury repair and fertility recovery. [PDF]

Bioact Mater
Zhang X, Wang S, Wang S, Long Z, Lu C, Wang J, Yang L, Yao C, He B, Chen X, Zhuang T, Xu X, Zheng Y.   +12 more
europepmc   +1 more source

Transdermal delivery of PeptiCRAd cancer vaccine using microneedle patches. [PDF]

Bioact Mater
D'Amico C, Fusciello M, Hamdan F, D'Alessio F, Bottega P, Saklauskaite M, Russo S, Cerioni J, Elbadri K, Kemell M, Hirvonen J, Cerullo V, Santos HA.   +12 more
europepmc   +1 more source

Development and optimization of raloxifene hydrochloride loaded lipid nanocapsule based hydrogel for transdermal delivery. [PDF]

Ther Deliv
Chaturvedi S, Gaur A, Garg A.
europepmc   +1 more source

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Transdermal carbon monoxide delivery

Journal of Controlled Release, 2023
Overuse injuries or acute trauma in joints often lead to painful tendinopathy, and pharmacological treatment effects are limited. The site of the disease is hard to reach with drugs, both systemically and through the skin. Therapeutic gases may close this gap, as they permeate easier through tissues than conventional small molecules. We present a patch
Matthias, Ruopp, Simon, Reiländer, Dorothee, Haas, Ignazio, Caruana, Daniel, Kronenberg, Wolfgang, Schmehl, Richard, Stange, Lorenz, Meinel   +7 more
openaire   +2 more sources

Transdermal peptide delivery

Biochemical Society Transactions, 1989
The transdermal delivery of peptide drugs, though ill-favoured by their hydrophilicity and high molecular mass, would seem very attractive from the pharmacotherapeutical and patient compliance point of view. In some cases, effective transdermal dosing has been achieved in vivo, especially with the aid of iontophoresis.
H E, Bodde, J C, Verhoef, M, Ponec
openaire   +2 more sources

Biocompatible Ionic Liquid-Mediated Micelles for Enhanced Transdermal Delivery of Paclitaxel.

ACS Applied Materials and Interfaces, 2021
Chemotherapeutic cytotoxic agents such as paclitaxel (PTX) are considered essential for the treatment of various cancers. However, PTX injection is associated with severe systemic side effects and high rates of patient noncompliance. Micelle formulations
Md. Korban Ali, Rahman Md Moshikur, R. Wakabayashi, M. Moniruzzaman, M. Goto   +4 more
semanticscholar   +1 more source