ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source
Fabrication and Evaluation of Dissolving Hyaluronic Acid Microneedle Patches for Minimally Invasive Transdermal Drug Delivery by Nanoimprinting. [PDF]
Miura S +12 more
europepmc +1 more source
Abstract Background Persons living with amyotrophic lateral sclerosis (PALS) are at high risk for malnutrition because of disease‐related factors such as dysphagia, self‐feeding difficulty, and hypermetabolism. Nutrition interventions, including enteral nutrition (EN) initiation after gastrostomy tube (G‐tube) placement, are integral to care but can ...
Stephanie Dobak +3 more
wiley +1 more source
Microneedles as transdermal drug delivery system for enhancing skin disease treatment. [PDF]
Wu C +5 more
europepmc +1 more source
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo +4 more
wiley +1 more source
Ultrasound Irradiation as a Candidate Procedure to Improve the Transdermal Drug Delivery to the Tail Edema of a Mouse Model. [PDF]
Kumegawa S +6 more
europepmc +1 more source
ABSTRACT Background The NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) study, led by the ESAIC Clinical Trials Network, collected prospective data on 5609 children up to 60 weeks postmenstrual age undergoing 6542 anesthetic procedures across 165 centers in 31 European countries (ESAIC_CTN_NECTARINE).
Claudia Neumann +4 more
wiley +1 more source
Formulation and Ex Vivo Evaluation of Ivermectin Within Different Nano-Drug Delivery Vehicles for Transdermal Drug Delivery. [PDF]
Steenekamp EM +3 more
europepmc +1 more source
3D printing redefines microneedle fabrication for transdermal drug delivery. [PDF]
Song KY, Zhang WJ, Behzadfar M.
europepmc +1 more source
Correction: Khalid et al. Development of Rapidly Dissolving Microneedles Integrated with Valsartan-Loaded Nanoliposomes for Transdermal Drug Delivery: In Vitro and Ex Vivo Evaluation. <i>Pharmaceutics</i> 2025, <i>17</i>, 483. [PDF]
Khalid R +4 more
europepmc +1 more source

