Results 241 to 250 of about 46,310 (300)

Refractory Motor Complications: Towards a Pragmatic Definition

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Georg Ebersbach, Tobias Warnecke
wiley   +1 more source

Transdermal Delivery of Drugs

Annual Review of Medicine, 1988
Transdermal drug delivery involves the continuous administration of therapeutic molecules through the skin. It has the advantage of maintaining constant drug plasma levels and improving patient compliance. Compared to the oral route, losses in bioavailability due to first-pass liver metabolism are reduced. This paper describes the theory of transdermal
L, Brown, R, Langer
openaire   +2 more sources

Transdermal drug delivery devices

Clinics in Dermatology, 1989
Abstract The concept of transdermal delivery is not new, but until recently, its therapeutic application was restricted to creams and ointments which are messy and difficult to apply uniformly to ensure reproducible dosing. In the late 1970s, technology was developed that permitted the construction of multicomponent devices embodying the ability to ...
P W, Ledger, K C, Nichols
openaire   +2 more sources

Transdermal Drug Delivery

2022
Being the largest and most accessible organ, the skin is an attractive target for drug delivery. However, the efficient barrier function of the stratum corneum presents a considerable challenge to the delivery of therapeutic into and across the skin. Nevertheless, years of research in the area of skin permeation culminated with the regulatory approval ...
Qonita Kurnia Anjani   +3 more
openaire   +1 more source

Transdermal Drug Delivery

2020
Transdermal drug delivery systems (TDDS), also known as “‘patches,”’ are dosage forms that provide a controlled release of therapeutically effective amount of drug across a patient’s skin. This chapter discusses the detailed aspects regarding concept of skin, drug penetration and drug kinetics, formulation and evaluation of TDDS, and its applications ...
Brahmeshwar Mishra, Gunjan Vasant Bonde
openaire   +2 more sources

Drug Delivery Systems. 6. Transdermal Drug Delivery

The Journal of Clinical Pharmacology, 1991
Transdermal drug delivery system has been in existence for a long time. In the past, the most commonly applied systems were topically applied creams and ointments for dermatological disorders. The occurrence of systemic side‐effects with some of these formulations is indicative of absorption through the skin.
openaire   +2 more sources

Transdermal Drug Delivery

2009
Transdermal drug delivery is a validated technology contributing significantly to global pharmaceutical care. Since 1980, impressive growth in this field has been observed with many commercial successes; importantly, a new chemical entity was recently developed and approved for transdermal administration without having first been given as an injectable
openaire   +2 more sources

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