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Transdermal Drug Delivery System
Asian Journal of Research in Pharmaceutical Sciences, 2023A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into systemic circulation. Often, this promotes healing to an injured area of the body. An advantage of a transdermal drug delivery route over other types of medication delivery such as oral, topical, intravenous ...
Nandkumar R. Kadam, Manisha M. Rokade
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Electrically-Assisted Transdermal Drug Delivery
Pharmaceutical Research, 1997Electrically-assisted transdermal delivery (EATDD) is the facilitated transport of compounds across the skin using an electromotive force. It has been extensively explored as a potential means for delivering peptides and other hydrophilic, acid-labile or orally unstable products of biotechnology. The predominant mechanism for delivery is iontophoresis,
J E, Riviere, M C, Heit
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Transdermal Drug Delivery: Useful Paradigms
Journal of Drug Targeting, 1995The successful development of transdermal delivery systems requires a systematic evaluation and understanding of a number of complex phenomena. For example, the study of drug transport through skin (and other biomembranes) has lead to a significant advance in our ability to select drugs which are appropriate for transdermal delivery.
R O, Potts, G W, Cleary
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Sonophoresis in transdermal drug deliverys
Ultrasonics, 2014Transdermal drug delivery (TDD) has several significant advantages compared to oral drug delivery, including elimination of pain and sustained drug release. However, the use of TDD is limited by low skin permeability due to the stratum corneum (SC), the outermost layer of the skin.
Donghee, Park +3 more
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Proniosomes in Transdermal Drug Delivery
Current Pharmaceutical Design, 2015Proniosomes are liquid crystalline-compact niosomal hybrid that can be hydrated to form niosomal dispersion instantly before use. It is a promising drug carrier with better physical and chemical stability than niosomes. Proniosomes have the potential to be scaled up for industrial purposes.
Yahya, Rahimpour +2 more
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Ultrasound and transdermal drug delivery
Drug Discovery Today, 2004Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injection. However, the stratum corneum acts as a barrier that limits the penetration of substances through the skin. Application of ultrasound to the skin increases its permeability (sonophoresis) and enables the delivery of ...
Ilana, Lavon, Joseph, Kost
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Microprocessor controlled transdermal drug delivery
International Journal of Pharmaceutics, 2006Transdermal drug delivery via iontophoresis is reviewed with special focus on the delivery of lidocaine for local anesthesia and fentanyl for patient controlled acute therapy such as postoperative pain. The role of the microprocessor controller in achieving dosimetry, alternating/reverse polarity, pre-programmed, and sensor-based delivery is ...
J Anand, Subramony +2 more
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Ultrasound mediated transdermal drug delivery
Advanced Drug Delivery Reviews, 2014Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injections. However, the stratum corneum serves as a barrier that limits the penetration of substances to the skin. Application of ultrasound (US) irradiation to the skin increases its permeability (sonophoresis) and enables ...
Aharon, Azagury +3 more
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Device-assisted transdermal drug delivery
Advanced Drug Delivery Reviews, 2018Transdermal drug delivery is a prospective drug delivery strategy to complement the limitations of conventional drug delivery systems including oral and injectable methods. This delivery route allows both convenient and painless drug delivery and a sustained release profile with reduced side effects.
Hyunjae Lee +5 more
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Transfersomes for transdermal drug delivery
Expert Opinion on Drug Delivery, 2006Transfersomes (Idea AG) are a form of elastic or deformable vesicle, which were first introduced in the early 1990s. Elasticity is generated by incorporation of an edge activator in the lipid bilayer structure. The original composition of these vesicles was soya phosphatidyl choline incorporating sodium cholate and a small concentration of ethanol ...
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